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** The Web's Daily Resource for ALS News
------------------------------------------------------------


** In the 01/14/2026 edition:
------------------------------------------------------------

*
** Managing decision-making fatigue with my 'two drawers' method (https://=
alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee792=
&id=3D760e1b03d0&e=3D006462e992)
------------------------------------------------------------


*
** First human trial begins in Europe for ALS=2C Parkinson's drug NRG5051=
 (https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd0=
0ea57ee792&id=3Dd85865ee88&e=3D006462e992)
------------------------------------------------------------





** Managing decision-making fatigue with my 'two drawers' method (https://=
alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee792=
&id=3D90bccbef23&e=3D006462e992)
------------------------------------------------------------
By Dagmar Munn on 01/14/2026
https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00e=
a57ee792&id=3Dd207a23068&e=3D006462e992

I=E2=80=99m always on the lookout for strategies to help my day-to-day lif=
e with ALS go more smoothly. Recently=2C I found a surprising spark of ins=
piration in a junk drawer in the kitchen. It wasn=E2=80=99t something hidi=
ng inside the drawer that helped; instead=2C it was my frustrating encount=
er with the mess itself that prompted a shift [=E2=80=A6]

The post Managing decision-making fatigue with my =E2=80=98two drawers=E2=
=80=99 method (https://alsnewstoday.us5.list-manage.com/track/click?u=3D52=
c64784d386bd00ea57ee792&id=3D499749e70d&e=3D006462e992) appeared fir=
st on ALS News Today (https://alsnewstoday.us5.list-manage.com/track/click=
?u=3D52c64784d386bd00ea57ee792&id=3Def34dde287&e=3D006462e992) .
Continue Reading (https://alsnewstoday.us5.list-manage.com/track/click?u=
=3D52c64784d386bd00ea57ee792&id=3Dd0bb7063d4&e=3D006462e992)



** First human trial begins in Europe for ALS=2C Parkinson's drug NRG5051=
 (https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd0=
0ea57ee792&id=3Da333d61706&e=3D006462e992)
------------------------------------------------------------
By Andrea Lobo=2C PhD on 01/14/2026
https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00e=
a57ee792&id=3D6359ccf059&e=3D006462e992

The first participants have been dosed in an early Phase 1 clinical study=
 that=E2=80=99s testing NRG5051=2C a first-in-class treatment candidate fo=
r amyotrophic lateral sclerosis (ALS) and Parkinson=E2=80=99s disease=2C i=
n healthy volunteers. Developed by NRG Therapeutics=2C the experimental th=
erapy is designed to restore the health of mitochondria=2C known as the po=
werhouses of cells. Mitochondria=2C which provide [=E2=80=A6]

The post First human trial begins in Europe for ALS=2C Parkinson=E2=80=99s=
 drug NRG5051 (https://alsnewstoday.us5.list-manage.com/track/click?u=3D52=
c64784d386bd00ea57ee792&id=3Db0d1f07d29&e=3D006462e992) appeared fir=
st on ALS News Today (https://alsnewstoday.us5.list-manage.com/track/click=
?u=3D52c64784d386bd00ea57ee792&id=3Dd02ee241c1&e=3D006462e992) .
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=3D52c64784d386bd00ea57ee792&id=3D761d4e2f92&e=3D006462e992)



** More Recent Articles:
------------------------------------------------------------
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** ALS Association fears 'instability' with removal of NINDS director (htt=
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0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
                    <tbody><tr>

                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding-top: 0;padding-right: 18px;padding-bottom: 9px;padding-left: 1=
8px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;word-break: break-word;color: #212121;font-family: 'Helv=
etica Neue'=2C Helvetica=2C Arial=2C Verdana=2C sans-serif;font-size: 15px=
;line-height: 150%;text-align: left;">

                            <h3 style=3D"display: block;margin: 0;padding:=
 0;color: #212121;font-family: 'Merriweather'=2C Georgia=2C 'Times New Rom=
an'=2C serif;font-size: 17px;font-style: normal;font-weight: bold;line-hei=
ght: 125%;letter-spacing: normal;text-align: left;"><strong>The Web's Dail=
y Resource for ALS News</strong></h3>

<h4 style=3D"display: block;margin: 0;padding: 0;color: #212121;font-famil=
y: 'Merriweather'=2C Georgia=2C 'Times New Roman'=2C serif;font-size: 16px=
;font-style: normal;font-weight: bold;line-height: 125%;letter-spacing: no=
rmal;text-align: left;"><strong>In the 01/14/2026 edition:</strong></h4>


<ul>
=09<li style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-=
webkit-text-size-adjust: 100%;">
=09<h2 class=3D"null" style=3D"display: block;margin: 0;padding: 0;color:=
 #212121;font-family: 'Merriweather'=2C Georgia=2C 'Times New Roman'=2C se=
rif;font-size: 17px;font-style: normal;font-weight: bold;line-height: 125%=
;letter-spacing: normal;text-align: left;"><span class=3D"mc-toc-title"><a=
 href=3D"https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784=
d386bd00ea57ee792&id=3De934b81561&e=3D006462e992" target=3D"_blank" style=
=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;color: #084c61;font-weight: normal;text-decoration: unde=
rline;">Managing decision-making fatigue with my 'two drawers' method</a><=
/span></h2>
=09</li>
</ul>
<span style=3D"font-size:16px"><span style=3D"font-family:merriweather=2Cg=
eorgia=2Ctimes new roman=2Cserif">

<ul>
=09<li style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-=
webkit-text-size-adjust: 100%;">
=09<h2 class=3D"null" style=3D"display: block;margin: 0;padding: 0;color:=
 #212121;font-family: 'Merriweather'=2C Georgia=2C 'Times New Roman'=2C se=
rif;font-size: 17px;font-style: normal;font-weight: bold;line-height: 125%=
;letter-spacing: normal;text-align: left;"><span class=3D"mc-toc-title"><a=
 href=3D"https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784=
d386bd00ea57ee792&id=3D8d58c5376d&e=3D006462e992" target=3D"_blank" style=
=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;color: #084c61;font-weight: normal;text-decoration: unde=
rline;">First human trial begins in Europe for ALS=2C Parkinson's drug NRG=
5051</a></span></h2>
=09</li>
</ul>
<span style=3D"font-size:16px"><span style=3D"font-family:merriweather=2Cg=
eorgia=2Ctimes new roman=2Cserif"> </span></span>
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=09=09=09=09<![endif]-->

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00%" class=3D"mcnDividerBlock" style=3D"min-width: 100%;border-collapse: c=
ollapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust:=
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              =09<!--[if mso]>
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=09=09=09=09<![endif]-->
                <table align=3D"left" border=3D"0" cellpadding=3D"0" cells=
pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
                    <tbody><tr>

                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding-top: 0;padding-right: 18px;padding-bottom: 9px;padding-left: 1=
8px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;word-break: break-word;color: #212121;font-family: 'Helv=
etica Neue'=2C Helvetica=2C Arial=2C Verdana=2C sans-serif;font-size: 15px=
;line-height: 150%;text-align: left;">

                            <div style=3D"text-align: left;"></div>

<h2 class=3D"mc-toc-title" style=3D"display: block;margin: 0;padding: 0;co=
lor: #212121;font-family: 'Merriweather'=2C Georgia=2C 'Times New Roman'=
=2C serif;font-size: 17px;font-style: normal;font-weight: bold;line-height=
: 125%;letter-spacing: normal;text-align: left;"><a href=3D"https://alsnew=
stoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D=
0e7722e158&e=3D006462e992" target=3D"_blank" style=3D"mso-line-height-rul=
e: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color=
: #084c61;font-weight: normal;text-decoration: underline;">Managing decisi=
on-making fatigue with my 'two drawers' method</a></h2>
<span style=3D"color:#033443"><em>By Dagmar Munn on </em></span><em>01/14/=
2026</em><br>
<span style=3D"color:#212121"><a href=3D"https://alsnewstoday.us5.list-man=
age.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3Dd16a75ca16&e=3D006462e992" title=3D"Managing decision-making fatigue with my =E2=80=98two dr=
awers=E2=80=99 method" rel=3D"nofollow" style=3D"mso-line-height-rule: exa=
ctly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #084=
c61;font-weight: normal;text-decoration: underline;"><img width=3D"800" sr=
c=3D"https://alsnewstoday.com/wp-content/uploads/2021/05/DagmarMunn_Living=
WellWithALS-1024x384.jpg" class=3D"webfeedsFeaturedVisual wp-post-image mc=
RssImage" alt=3D"banner for &quot;Living Well With ALS&quot; by Dagmar Mun=
n" style=3D"max-width: 100%;width: 100%;padding-bottom: 0;display: inline;=
vertical-align: bottom;border: 0;height: auto;outline: none;text-decoratio=
n: none;-ms-interpolation-mode: bicubic;" link_thumbnail=3D"1" decoding=3D=
"async" loading=3D"lazy" srcset=3D"https://alsnewstoday.com/wp-content/upl=
oads/2021/05/DagmarMunn_LivingWellWithALS-1024x384.jpg 1024w=2C https://al=
snewstoday.com/wp-content/uploads/2021/05/DagmarMunn_LivingWellWithALS-300=
x113.jpg 300w=2C https://alsnewstoday.com/wp-content/uploads/2021/05/Dagma=
rMunn_LivingWellWithALS-768x288.jpg 768w=2C https://alsnewstoday.com/wp-co=
ntent/uploads/2021/05/DagmarMunn_LivingWellWithALS-1200x450.jpg 1200w=2C h=
ttps://alsnewstoday.com/wp-content/uploads/2021/05/DagmarMunn_LivingWellWi=
thALS.jpg 1400w" sizes=3D"(max-width: 800px) 100vw=2C 800px" data-wp-pid=
=3D"41259" border=3D"0"></a><p style=3D"margin: 10px 0;padding: 0;mso-line=
-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust:=
 100%;color: #212121;font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C Verdana=2C sans-serif;font-size: 15px;line-height: 150%;text-align: le=
ft;">I=E2=80=99m always on the lookout for strategies to help my day-to-da=
y life with ALS go more smoothly. Recently=2C I found a surprising spark o=
f inspiration in a junk drawer in the kitchen. It wasn=E2=80=99t something=
 hiding inside the drawer that helped; instead=2C it was my frustrating en=
counter with the mess itself that prompted a shift [&#8230;]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #212121;font-fa=
mily: 'Helvetica Neue'=2C Helvetica=2C Arial=2C Verdana=2C sans-serif;font=
-size: 15px;line-height: 150%;text-align: left;">The post <a href=3D"https=
://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee=
792&id=3D3c2724e9bd&e=3D006462e992" style=3D"mso-line-height-rule: exactl=
y;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #084c61=
;font-weight: normal;text-decoration: underline;">Managing decision-making=
 fatigue with my &#8216;two drawers&#8217; method</a> appeared first on <a=
 href=3D"https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784=
d386bd00ea57ee792&id=3D9c0781d2f8&e=3D006462e992" style=3D"mso-line-heigh=
t-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;=
color: #084c61;font-weight: normal;text-decoration: underline;">ALS News T=
oday</a>.</p></span>
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e-adjust: 100%;">
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lank" style=3D"font-weight: bold;letter-spacing: normal;line-height: 100%;=
text-align: center;text-decoration: none;color: #084C61;mso-line-height-ru=
le: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;disp=
lay: block;">Continue Reading</a>
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t-text-size-adjust: 100%;">
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=09=09=09=09<![endif]-->
                <table align=3D"left" border=3D"0" cellpadding=3D"0" cells=
pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
                    <tbody><tr>

                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding: 0px 18px 9px;text-align: left;mso-line-height-rule: exactly;-=
ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;word-break: break=
-word;color: #212121;font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C Verdana=2C sans-serif;font-size: 15px;line-height: 150%;">



<h2 class=3D"mc-toc-title" style=3D"display: block;margin: 0;padding: 0;co=
lor: #212121;font-family: 'Merriweather'=2C Georgia=2C 'Times New Roman'=
=2C serif;font-size: 17px;font-style: normal;font-weight: bold;line-height=
: 125%;letter-spacing: normal;text-align: left;"><a href=3D"https://alsnew=
stoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D=
a6bc268f59&e=3D006462e992" target=3D"_blank" style=3D"mso-line-height-rul=
e: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color=
: #084c61;font-weight: normal;text-decoration: underline;">First human tri=
al begins in Europe for ALS=2C Parkinson's drug NRG5051</a></h2>
<span style=3D"color:#033443"><em>By Andrea Lobo=2C PhD on </em></span><em=
>01/14/2026</em><br>
<span style=3D"color:#212121"><a href=3D"https://alsnewstoday.us5.list-man=
age.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3Db5021943f3&e=3D006462e992" title=3D"First human trial begins in Europe for ALS=2C Parkinson=
=E2=80=99s drug NRG5051" rel=3D"nofollow" style=3D"mso-line-height-rule: e=
xactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #0=
84c61;font-weight: normal;text-decoration: underline;"><img width=3D"700"=
 src=3D"https://alsnewstoday.com/wp-content/uploads/2021/10/Mitochondria.p=
ng" class=3D"webfeedsFeaturedVisual wp-post-image mcRssImage" alt=3D"An il=
lustration provides a close-up view of mitochondria=2C the powerhouses of=
 cells." style=3D"max-width: 100%;width: 100%;padding-bottom: 0;display: i=
nline;vertical-align: bottom;border: 0;height: auto;outline: none;text-dec=
oration: none;-ms-interpolation-mode: bicubic;" link_thumbnail=3D"1" decod=
ing=3D"async" loading=3D"lazy" srcset=3D"https://alsnewstoday.com/wp-conte=
nt/uploads/2021/10/Mitochondria.png 700w=2C https://alsnewstoday.com/wp-co=
ntent/uploads/2021/10/Mitochondria-380x190.png 380w" sizes=3D"(max-width:=
 700px) 100vw=2C 700px" data-wp-pid=3D"73231" border=3D"0"></a><p style=3D=
"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-text-size-adj=
ust: 100%;-webkit-text-size-adjust: 100%;color: #212121;font-family: 'Helv=
etica Neue'=2C Helvetica=2C Arial=2C Verdana=2C sans-serif;font-size: 15px=
;line-height: 150%;text-align: left;">The first participants have been dos=
ed in an early Phase 1 clinical study that&#8217;s testing NRG5051=2C a fi=
rst-in-class treatment candidate for amyotrophic lateral sclerosis (ALS) a=
nd Parkinson&#8217;s disease=2C in healthy volunteers. Developed by NRG Th=
erapeutics=2C the experimental therapy is designed to restore the health o=
f mitochondria=2C known as the powerhouses of cells. Mitochondria=2C which=
 provide [&#8230;]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #212121;font-fa=
mily: 'Helvetica Neue'=2C Helvetica=2C Arial=2C Verdana=2C sans-serif;font=
-size: 15px;line-height: 150%;text-align: left;">The post <a href=3D"https=
://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee=
792&id=3D25ede8a322&e=3D006462e992" style=3D"mso-line-height-rule: exactl=
y;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #084c61=
;font-weight: normal;text-decoration: underline;">First human trial begins=
 in Europe for ALS=2C Parkinson&#8217;s drug NRG5051</a> appeared first on=
 <a href=3D"https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64=
784d386bd00ea57ee792&id=3D46796c8a0b&e=3D006462e992" style=3D"mso-line-he=
ight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 10=
0%;color: #084c61;font-weight: normal;text-decoration: underline;">ALS New=
s Today</a>.</p></span>
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<h3 class=3D"null" style=3D"display: block;margin: 0;padding: 0;color: #21=
2121;font-family: 'Merriweather'=2C Georgia=2C 'Times New Roman'=2C serif;=
font-size: 17px;font-style: normal;font-weight: bold;line-height: 125%;let=
ter-spacing: normal;text-align: left;">More Recent Articles:</h3>
<a rel=3D"nofollow" target=3D"_blank" href=3D"https://alsnewstoday.us5.lis=
t-manage.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3Dc17d651397&e=
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y;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #084c61=
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ng TDP-43 protein put on FDA fast track</a><br><a rel=3D"nofollow" target=
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coration: underline;">ALS Association fears 'instability' with removal of=
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792&id=3Df2574cce2e&e=3D006462e992" class=3D"rss-recent" style=3D"mso-lin=
e-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust=
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rture advances RNA-targeting treatment for ALS</a><br><a rel=3D"nofollow"=
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click?u=3D52c64784d386bd00ea57ee792&id=3D1adcac9401&e=3D006462e992" class=
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t: 100%;-webkit-text-size-adjust: 100%;color: #084c61;font-weight: normal;=
text-decoration: underline;">The ongoing turnover of ALS caregivers is cha=
llenging to manage</a><br><a rel=3D"nofollow" target=3D"_blank" href=3D"ht=
tps://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea5=
7ee792&id=3D98f82dbdff&e=3D006462e992" class=3D"rss-recent" style=3D"mso-=
line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adj=
ust: 100%;color: #084c61;font-weight: normal;text-decoration: underline;">=
Shionogi strengthens rare disease strategy with planned Radicava deal</a>
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tent" style=3D"padding: 18px;color: #FFFFFF;font-family: Helvetica;font-si=
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tly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;word-break:=
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                                        <h3 class=3D"null" style=3D"text-a=
lign: center;display: block;margin: 0;padding: 0;color: #212121;font-famil=
y: 'Merriweather'=2C Georgia=2C 'Times New Roman'=2C serif;font-size: 17px=
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                                                    <td valign=3D"top" sty=
le=3D"padding-right: 10px;padding-bottom: 9px;mso-line-height-rule: exactl=
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00%" class=3D"mcnBoxedTextBlock" style=3D"min-width: 100%;border-collapse:=
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adjust: 100%;">

=09=09=09=09<!--[if gte mso 9]>
=09=09=09=09<td align=3D"center" valign=3D"top" ">
=09=09=09=09<![endif]-->
                <table align=3D"left" border=3D"0" cellpadding=3D"0" cells=
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apse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 100=
%;-webkit-text-size-adjust: 100%;float: left;" class=3D"mcnBoxedTextConten=
tContainer">
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                        <td style=3D"padding-top: 9px;padding-left: 18px;p=
adding-bottom: 9px;padding-right: 18px;mso-line-height-rule: exactly;-ms-t=
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"mcnTextContentContainer" width=3D"100%" style=3D"min-width: 100% !importa=
nt;background-color: #084C61;border-collapse: collapse;mso-table-lspace: 0=
pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adju=
st: 100%;">
                                <tbody><tr>
                                    <td valign=3D"top" class=3D"mcnTextCon=
tent" style=3D"padding: 18px;color: #FFFFFF;font-family: Helvetica;font-si=
ze: 12px;font-weight: normal;text-align: center;mso-line-height-rule: exac=
tly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;word-break:=
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