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** The Web's Daily Resource for ALS News
------------------------------------------------------------


** In the 01/16/2026 edition:
------------------------------------------------------------

*
** The stress of caregiving and grief led to brain fog I didn't notice at=
 first (https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d=
386bd00ea57ee792&id=3D1e3159bb8b&e=3D006462e992)
------------------------------------------------------------


*
** 1st patient dosed in Phase 2 trial of SOD1-ALS treatment RAG-17 (https:=
//alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee7=
92&id=3D1eee0e8fae&e=3D006462e992)
------------------------------------------------------------


*
** What my journals reveal about my journey as an ALS caregiver (https://a=
lsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee792&=
id=3D7f672aa888&e=3D006462e992)
------------------------------------------------------------


*
** Clene=2C FDA to discuss survival data and approval path for CNM-Au8 (ht=
tps://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea5=
7ee792&id=3D9c34e1a3fd&e=3D006462e992)
------------------------------------------------------------





** The stress of caregiving and grief led to brain fog I didn't notice at=
 first (https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d=
386bd00ea57ee792&id=3Db806d61146&e=3D006462e992)
------------------------------------------------------------
By Juliet Taylor on 01/16/2026
https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00e=
a57ee792&id=3D2aaaa63465&e=3D006462e992

When my late husband=2C Jeff=2C was diagnosed with ALS in 2018=2C I knew i=
t would bring emotional challenges for both of us. I expected =E2=80=94 co=
rrectly=2C as it turns out =E2=80=94 that we=E2=80=99d feel scared=2C anxi=
ous=2C and sad. I recognized the immediate and lingering shock it brought=
 in different ways. What I hadn=E2=80=99t expected=2C and [=E2=80=A6]

The post The stress of caregiving and grief led to brain fog I didn=E2=80=
=99t notice at first (https://alsnewstoday.us5.list-manage.com/track/click=
?u=3D52c64784d386bd00ea57ee792&id=3D154231d794&e=3D006462e992) appea=
red first on ALS News Today (https://alsnewstoday.us5.list-manage.com/trac=
k/click?u=3D52c64784d386bd00ea57ee792&id=3Dfda9df3be7&e=3D006462e992=
) .
Continue Reading (https://alsnewstoday.us5.list-manage.com/track/click?u=
=3D52c64784d386bd00ea57ee792&id=3D57fab6e41c&e=3D006462e992)



** 1st patient dosed in Phase 2 trial of SOD1-ALS treatment RAG-17 (https:=
//alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee7=
92&id=3Dd22f824e07&e=3D006462e992)
------------------------------------------------------------
By Andrea Lobo=2C PhD on 01/16/2026
https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00e=
a57ee792&id=3Da0430fb0d6&e=3D006462e992

The first patient has been dosed in a Phase 2 clinical study testing RAG-1=
7=2C a therapy being developed by Ractigen Therapeutics for people with am=
yotrophic lateral sclerosis (ALS) who carry mutations in the SOD1 gene (SO=
D1-ALS). The progression into the Phase 2 portion of the trial follows the=
 successful completion of a Phase 1 trial [=E2=80=A6]

The post 1st patient dosed in Phase 2 trial of SOD1-ALS treatment RAG-17 (=
https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00e=
a57ee792&id=3D7c507823dc&e=3D006462e992) appeared first on ALS News=
 Today (https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d=
386bd00ea57ee792&id=3D3807a0371e&e=3D006462e992) .
Continue Reading (https://alsnewstoday.us5.list-manage.com/track/click?u=
=3D52c64784d386bd00ea57ee792&id=3D1547913cf8&e=3D006462e992)



** What my journals reveal about my journey as an ALS caregiver (https://a=
lsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee792&=
id=3D6bc6fddd8f&e=3D006462e992)
------------------------------------------------------------
By Kristin Neva on 01/15/2026
https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00e=
a57ee792&id=3Decb4aab028&e=3D006462e992

Every step of an ALS journey is difficult=2C but somehow we=E2=80=99re wir=
ed with the ability to forget much of the pain and remember the good. I wr=
ote last week about our current challenge of finding nighttime caregivers.=
 After getting all of the shifts covered=2C one of our caregivers who had=
 picked up an additional night [=E2=80=A6]

The post What my journals reveal about my journey as an ALS caregiver (htt=
ps://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57=
ee792&id=3D99fe60ccfa&e=3D006462e992) appeared first on ALS News Tod=
ay (https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386b=
d00ea57ee792&id=3Da1a9e23b2f&e=3D006462e992) .
Continue Reading (https://alsnewstoday.us5.list-manage.com/track/click?u=
=3D52c64784d386bd00ea57ee792&id=3Dc525864c4b&e=3D006462e992)



** Clene=2C FDA to discuss survival data and approval path for CNM-Au8 (ht=
tps://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea5=
7ee792&id=3Dce2981b651&e=3D006462e992)
------------------------------------------------------------
By Marisa Wexler=2C MS on 01/15/2026
https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00e=
a57ee792&id=3De9a9720431&e=3D006462e992

Clene is scheduled to meet with the U.S. Food and Drug Administration (FDA=
) in the coming months to discuss new data and a potential path toward acc=
elerated approval for CNM-Au8=2C an oral therapy being developed for amyot=
rophic lateral sclerosis (ALS). The company plans to argue that the treatm=
ent=E2=80=99s ability to lower key markers of nerve [=E2=80=A6]

The post Clene=2C FDA to discuss survival data and approval path for CNM-A=
u8 (https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386b=
d00ea57ee792&id=3D8f62caa90f&e=3D006462e992) appeared first on ALS N=
ews Today (https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c647=
84d386bd00ea57ee792&id=3Dec9046c303&e=3D006462e992) .
Continue Reading (https://alsnewstoday.us5.list-manage.com/track/click?u=
=3D52c64784d386bd00ea57ee792&id=3D47e0ca20cf&e=3D006462e992)



** More Recent Articles:
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** First human trial begins in Europe for ALS=2C Parkinson's drug NRG5051=
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** ALS gene therapy targeting TDP-43 protein put on FDA fast track (https:=
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** ALS Association fears 'instability' with removal of NINDS director (htt=
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** Aperture advances RNA-targeting treatment for ALS (https://alsnewstoday=
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er" style=3D"border-collapse: collapse;mso-table-lspace: 0pt;mso-table-rsp=
ace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;max-wid=
th: 600px !important;">
                                        <tr>
                                            <td valign=3D"top" class=3D"he=
aderContainer" style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust=
: 100%;-webkit-text-size-adjust: 100%;"></td>
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                                    <![endif]-->
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                            <tr>
                                <td align=3D"center" valign=3D"top" id=3D"=
templateBody" style=3D"background: #transparent none no-repeat center/cove=
r;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-si=
ze-adjust: 100%;background-color: #transparent;background-image: none;back=
ground-repeat: no-repeat;background-position: center;background-size: cove=
r;border-top: 0;border-bottom: 0;padding-top: 9px;padding-bottom: 9px;">
                                    <!--[if (gte mso 9)|(IE)]>
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ellspacing=3D"0" cellpadding=3D"0" width=3D"600" style=3D"width:600px;">
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dth=3D"600" style=3D"width:600px;">
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                                    <table align=3D"center" border=3D"0" c=
ellpadding=3D"0" cellspacing=3D"0" width=3D"100%" class=3D"templateContain=
er" style=3D"border-collapse: collapse;mso-table-lspace: 0pt;mso-table-rsp=
ace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;max-wid=
th: 600px !important;">
                                        <tr>
                                            <td valign=3D"top" class=3D"bo=
dyContainer" style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust:=
 100%;-webkit-text-size-adjust: 100%;"><table border=3D"0" cellpadding=3D"=
0" cellspacing=3D"0" width=3D"100%" class=3D"mcnTextBlock" style=3D"min-wi=
dth: 100%;border-collapse: collapse;mso-table-lspace: 0pt;mso-table-rspace=
: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
    <tbody class=3D"mcnTextBlockOuter">
        <tr>
            <td valign=3D"top" class=3D"mcnTextBlockInner" style=3D"paddin=
g-top: 9px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webki=
t-text-size-adjust: 100%;">
              =09<!--[if mso]>
=09=09=09=09<table align=3D"left" border=3D"0" cellspacing=3D"0" cellpaddi=
ng=3D"0" width=3D"100%" style=3D"width:100%;">
=09=09=09=09<tr>
=09=09=09=09<![endif]-->
=09=09=09
=09=09=09=09<!--[if mso]>
=09=09=09=09<td valign=3D"top" width=3D"NaN" style=3D"width:NaNpx;">
=09=09=09=09<![endif]-->
                <table align=3D"left" border=3D"0" cellpadding=3D"0" cells=
pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
                    <tbody><tr>

                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding-top: 0;padding-right: 18px;padding-bottom: 9px;padding-left: 1=
8px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;word-break: break-word;color: #212121;font-family: 'Helv=
etica Neue'=2C Helvetica=2C Arial=2C Verdana=2C sans-serif;font-size: 15px=
;line-height: 150%;text-align: left;">

                            <h3 style=3D"display: block;margin: 0;padding:=
 0;color: #212121;font-family: 'Merriweather'=2C Georgia=2C 'Times New Rom=
an'=2C serif;font-size: 17px;font-style: normal;font-weight: bold;line-hei=
ght: 125%;letter-spacing: normal;text-align: left;"><strong>The Web's Dail=
y Resource for ALS News</strong></h3>

<h4 style=3D"display: block;margin: 0;padding: 0;color: #212121;font-famil=
y: 'Merriweather'=2C Georgia=2C 'Times New Roman'=2C serif;font-size: 16px=
;font-style: normal;font-weight: bold;line-height: 125%;letter-spacing: no=
rmal;text-align: left;"><strong>In the 01/16/2026 edition:</strong></h4>


<ul>
=09<li style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-=
webkit-text-size-adjust: 100%;">
=09<h2 class=3D"null" style=3D"display: block;margin: 0;padding: 0;color:=
 #212121;font-family: 'Merriweather'=2C Georgia=2C 'Times New Roman'=2C se=
rif;font-size: 17px;font-style: normal;font-weight: bold;line-height: 125%=
;letter-spacing: normal;text-align: left;"><span class=3D"mc-toc-title"><a=
 href=3D"https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784=
d386bd00ea57ee792&id=3D035b1d2450&e=3D006462e992" target=3D"_blank" style=
=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;color: #084c61;font-weight: normal;text-decoration: unde=
rline;">The stress of caregiving and grief led to brain fog I didn't notic=
e at first</a></span></h2>
=09</li>
</ul>
<span style=3D"font-size:16px"><span style=3D"font-family:merriweather=2Cg=
eorgia=2Ctimes new roman=2Cserif">

<ul>
=09<li style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-=
webkit-text-size-adjust: 100%;">
=09<h2 class=3D"null" style=3D"display: block;margin: 0;padding: 0;color:=
 #212121;font-family: 'Merriweather'=2C Georgia=2C 'Times New Roman'=2C se=
rif;font-size: 17px;font-style: normal;font-weight: bold;line-height: 125%=
;letter-spacing: normal;text-align: left;"><span class=3D"mc-toc-title"><a=
 href=3D"https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784=
d386bd00ea57ee792&id=3Dc8888ec9a8&e=3D006462e992" target=3D"_blank" style=
=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;color: #084c61;font-weight: normal;text-decoration: unde=
rline;">1st patient dosed in Phase 2 trial of SOD1-ALS treatment RAG-17</a=
></span></h2>
=09</li>
</ul>
<span style=3D"font-size:16px"><span style=3D"font-family:merriweather=2Cg=
eorgia=2Ctimes new roman=2Cserif">

<ul>
=09<li style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-=
webkit-text-size-adjust: 100%;">
=09<h2 class=3D"null" style=3D"display: block;margin: 0;padding: 0;color:=
 #212121;font-family: 'Merriweather'=2C Georgia=2C 'Times New Roman'=2C se=
rif;font-size: 17px;font-style: normal;font-weight: bold;line-height: 125%=
;letter-spacing: normal;text-align: left;"><span class=3D"mc-toc-title"><a=
 href=3D"https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784=
d386bd00ea57ee792&id=3Da80d671f75&e=3D006462e992" target=3D"_blank" style=
=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;color: #084c61;font-weight: normal;text-decoration: unde=
rline;">What my journals reveal about my journey as an ALS caregiver</a></=
span></h2>
=09</li>
</ul>
<span style=3D"font-size:16px"><span style=3D"font-family:merriweather=2Cg=
eorgia=2Ctimes new roman=2Cserif">

<ul>
=09<li style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-=
webkit-text-size-adjust: 100%;">
=09<h2 class=3D"null" style=3D"display: block;margin: 0;padding: 0;color:=
 #212121;font-family: 'Merriweather'=2C Georgia=2C 'Times New Roman'=2C se=
rif;font-size: 17px;font-style: normal;font-weight: bold;line-height: 125%=
;letter-spacing: normal;text-align: left;"><span class=3D"mc-toc-title"><a=
 href=3D"https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784=
d386bd00ea57ee792&id=3Deb2eaaa03a&e=3D006462e992" target=3D"_blank" style=
=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;color: #084c61;font-weight: normal;text-decoration: unde=
rline;">Clene=2C FDA to discuss survival data and approval path for CNM-Au=
8</a></span></h2>
=09</li>
</ul>
<span style=3D"font-size:16px"><span style=3D"font-family:merriweather=2Cg=
eorgia=2Ctimes new roman=2Cserif"> </span></span>
                        </span></span></span></span></span></span></td>
                    </tr>
                </tbody></table>
=09=09=09=09<!--[if mso]>
=09=09=09=09</td>
=09=09=09=09<![endif]-->

=09=09=09=09<!--[if mso]>
=09=09=09=09</tr>
=09=09=09=09</table>
=09=09=09=09<![endif]-->
            </td>
        </tr>
    </tbody>
</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnDividerBlock" style=3D"min-width: 100%;border-collapse: c=
ollapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust:=
 100%;-webkit-text-size-adjust: 100%;table-layout: fixed !important;">
    <tbody class=3D"mcnDividerBlockOuter">
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            <td class=3D"mcnDividerBlockInner" style=3D"min-width: 100%;pa=
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                <table class=3D"mcnDividerContent" border=3D"0" cellpaddin=
g=3D"0" cellspacing=3D"0" width=3D"100%" style=3D"min-width: 100%;border-t=
op-width: 1px;border-top-style: solid;border-top-color: #D7D7D7;border-col=
lapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-=
adjust: 100%;-webkit-text-size-adjust: 100%;">
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</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnTextBlock" style=3D"min-width: 100%;border-collapse: coll=
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g-top: 9px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webki=
t-text-size-adjust: 100%;">
              =09<!--[if mso]>
=09=09=09=09<table align=3D"left" border=3D"0" cellspacing=3D"0" cellpaddi=
ng=3D"0" width=3D"100%" style=3D"width:100%;">
=09=09=09=09<tr>
=09=09=09=09<![endif]-->
=09=09=09
=09=09=09=09<!--[if mso]>
=09=09=09=09<td valign=3D"top" width=3D"600" style=3D"width:600px;">
=09=09=09=09<![endif]-->
                <table align=3D"left" border=3D"0" cellpadding=3D"0" cells=
pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
                    <tbody><tr>

                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding-top: 0;padding-right: 18px;padding-bottom: 9px;padding-left: 1=
8px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;word-break: break-word;color: #212121;font-family: 'Helv=
etica Neue'=2C Helvetica=2C Arial=2C Verdana=2C sans-serif;font-size: 15px=
;line-height: 150%;text-align: left;">

                            <div style=3D"text-align: left;"></div>

<h2 class=3D"mc-toc-title" style=3D"display: block;margin: 0;padding: 0;co=
lor: #212121;font-family: 'Merriweather'=2C Georgia=2C 'Times New Roman'=
=2C serif;font-size: 17px;font-style: normal;font-weight: bold;line-height=
: 125%;letter-spacing: normal;text-align: left;"><a href=3D"https://alsnew=
stoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D=
c1c05d1d47&e=3D006462e992" target=3D"_blank" style=3D"mso-line-height-rul=
e: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color=
: #084c61;font-weight: normal;text-decoration: underline;">The stress of c=
aregiving and grief led to brain fog I didn't notice at first</a></h2>
<span style=3D"color:#033443"><em>By Juliet Taylor on </em></span><em>01/1=
6/2026</em><br>
<span style=3D"color:#212121"><a href=3D"https://alsnewstoday.us5.list-man=
age.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3Da7e09647c2&e=3D006462e992" title=3D"The stress of caregiving and grief led to brain fog I di=
dn=E2=80=99t notice at first" rel=3D"nofollow" style=3D"mso-line-height-ru=
le: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;colo=
r: #084c61;font-weight: normal;text-decoration: underline;"><img width=3D"=
800" src=3D"https://alsnewstoday.com/wp-content/uploads/2022/08/JulietTayl=
or_ThunderRoad-800x300.jpg" class=3D"webfeedsFeaturedVisual wp-post-image=
 mcRssImage" alt=3D"Banner for Juliet Taylor's column &quot;Thunder Road.&=
quot; The graphic depicts a couple on a pier overlooking a lake=2C mountai=
ns=2C and forest." style=3D"max-width: 100%;width: 100%;padding-bottom: 0;=
display: inline;vertical-align: bottom;border: 0;height: auto;outline: non=
e;text-decoration: none;-ms-interpolation-mode: bicubic;" link_thumbnail=
=3D"1" decoding=3D"async" loading=3D"lazy" srcset=3D"https://alsnewstoday.=
com/wp-content/uploads/2022/08/JulietTaylor_ThunderRoad-800x300.jpg 800w=
=2C https://alsnewstoday.com/wp-content/uploads/2022/08/JulietTaylor_Thund=
erRoad-380x143.jpg 380w=2C https://alsnewstoday.com/wp-content/uploads/202=
2/08/JulietTaylor_ThunderRoad-768x288.jpg 768w=2C https://alsnewstoday.com=
/wp-content/uploads/2022/08/JulietTaylor_ThunderRoad-1536x576.jpg 1536w=2C=
 https://alsnewstoday.com/wp-content/uploads/2022/08/JulietTaylor_ThunderR=
oad-1200x450.jpg 1200w=2C https://alsnewstoday.com/wp-content/uploads/2022=
/08/JulietTaylor_ThunderRoad.jpg 1800w" sizes=3D"(max-width: 800px) 100vw=
=2C 800px" data-wp-pid=3D"78933" border=3D"0"></a><p style=3D"margin: 10px=
 0;padding: 0;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-we=
bkit-text-size-adjust: 100%;color: #212121;font-family: 'Helvetica Neue'=
=2C Helvetica=2C Arial=2C Verdana=2C sans-serif;font-size: 15px;line-heigh=
t: 150%;text-align: left;">When my late husband=2C Jeff=2C was diagnosed w=
ith ALS in 2018=2C I knew it would bring emotional challenges for both of=
 us. I expected =E2=80=94 correctly=2C as it turns out =E2=80=94 that we=
=E2=80=99d feel scared=2C anxious=2C and sad. I recognized the immediate a=
nd lingering shock it brought in different ways. What I hadn=E2=80=99t exp=
ected=2C and [&#8230;]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #212121;font-fa=
mily: 'Helvetica Neue'=2C Helvetica=2C Arial=2C Verdana=2C sans-serif;font=
-size: 15px;line-height: 150%;text-align: left;">The post <a href=3D"https=
://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee=
792&id=3Dbe9c94ebf2&e=3D006462e992" style=3D"mso-line-height-rule: exactl=
y;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #084c61=
;font-weight: normal;text-decoration: underline;">The stress of caregiving=
 and grief led to brain fog I didn&#8217;t notice at first</a> appeared fi=
rst on <a href=3D"https://alsnewstoday.us5.list-manage.com/track/click?u=
=3D52c64784d386bd00ea57ee792&id=3Dc16881e048&e=3D006462e992" style=3D"mso=
-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-ad=
just: 100%;color: #084c61;font-weight: normal;text-decoration: underline;"=
>ALS News Today</a>.</p></span>
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=09=09=09=09<!--[if mso]>
=09=09=09=09</td>
=09=09=09=09<![endif]-->

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00%" class=3D"mcnButtonBlock" style=3D"min-width: 100%;border-collapse: co=
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00%;-webkit-text-size-adjust: 100%;">
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            <td style=3D"padding-top: 0;padding-right: 18px;padding-bottom=
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;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-siz=
e-adjust: 100%;">
                                <a class=3D"mcnButton " title=3D"Continue=
 Reading" href=3D"https://alsnewstoday.us5.list-manage.com/track/click?u=
=3D52c64784d386bd00ea57ee792&id=3Df922ef012f&e=3D006462e992" target=3D"_b=
lank" style=3D"font-weight: bold;letter-spacing: normal;line-height: 100%;=
text-align: center;text-decoration: none;color: #084C61;mso-line-height-ru=
le: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;disp=
lay: block;">Continue Reading</a>
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</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnTextBlock" style=3D"min-width: 100%;border-collapse: coll=
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g-top: 9px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webki=
t-text-size-adjust: 100%;">
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=09=09=09=09<![endif]-->
                <table align=3D"left" border=3D"0" cellpadding=3D"0" cells=
pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
                    <tbody><tr>

                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding: 0px 18px 9px;text-align: left;mso-line-height-rule: exactly;-=
ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;word-break: break=
-word;color: #212121;font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C Verdana=2C sans-serif;font-size: 15px;line-height: 150%;">



<h2 class=3D"mc-toc-title" style=3D"display: block;margin: 0;padding: 0;co=
lor: #212121;font-family: 'Merriweather'=2C Georgia=2C 'Times New Roman'=
=2C serif;font-size: 17px;font-style: normal;font-weight: bold;line-height=
: 125%;letter-spacing: normal;text-align: left;"><a href=3D"https://alsnew=
stoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D=
8207abc7fa&e=3D006462e992" target=3D"_blank" style=3D"mso-line-height-rul=
e: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color=
: #084c61;font-weight: normal;text-decoration: underline;">1st patient dos=
ed in Phase 2 trial of SOD1-ALS treatment RAG-17</a></h2>
<span style=3D"color:#033443"><em>By Andrea Lobo=2C PhD on </em></span><em=
>01/16/2026</em><br>
<span style=3D"color:#212121"><a href=3D"https://alsnewstoday.us5.list-man=
age.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D2c5bfe5bf6&e=3D006462e992" title=3D"1st patient dosed in Phase 2 trial of SOD1-ALS treatment=
 RAG-17" rel=3D"nofollow" style=3D"mso-line-height-rule: exactly;-ms-text-=
size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #084c61;font-weigh=
t: normal;text-decoration: underline;"><img width=3D"700" src=3D"https://a=
lsnewstoday.com/wp-content/uploads/2023/06/ClinicalTrials-1.png" class=3D"=
webfeedsFeaturedVisual wp-post-image mcRssImage" alt=3D"The words &quot;CL=
INICAL TRIALS&quot; are pictured between a handful of oral medications on=
 top and a heart rate monitor graph on bottom." style=3D"max-width: 100%;w=
idth: 100%;padding-bottom: 0;display: inline;vertical-align: bottom;border=
: 0;height: auto;outline: none;text-decoration: none;-ms-interpolation-mod=
e: bicubic;" link_thumbnail=3D"1" decoding=3D"async" loading=3D"lazy" srcs=
et=3D"https://alsnewstoday.com/wp-content/uploads/2023/06/ClinicalTrials-1=
=2Epng 700w=2C https://alsnewstoday.com/wp-content/uploads/2023/06/ClinicalT=
rials-1-380x190.png 380w" sizes=3D"(max-width: 700px) 100vw=2C 700px" data=
-wp-pid=3D"85148" border=3D"0"></a><p style=3D"margin: 10px 0;padding: 0;m=
so-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-=
adjust: 100%;color: #212121;font-family: 'Helvetica Neue'=2C Helvetica=2C=
 Arial=2C Verdana=2C sans-serif;font-size: 15px;line-height: 150%;text-ali=
gn: left;">The first patient has been dosed in a Phase 2 clinical study te=
sting RAG-17=2C a therapy being developed by Ractigen Therapeutics for peo=
ple with amyotrophic lateral sclerosis (ALS) who carry mutations in the SO=
D1 gene (SOD1-ALS). The progression into the Phase 2 portion of the trial=
 follows the successful completion of a Phase 1 trial [&#8230;]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #212121;font-fa=
mily: 'Helvetica Neue'=2C Helvetica=2C Arial=2C Verdana=2C sans-serif;font=
-size: 15px;line-height: 150%;text-align: left;">The post <a href=3D"https=
://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee=
792&id=3Df4db957cbb&e=3D006462e992" style=3D"mso-line-height-rule: exactl=
y;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #084c61=
;font-weight: normal;text-decoration: underline;">1st patient dosed in Pha=
se 2 trial of SOD1-ALS treatment RAG-17</a> appeared first on <a href=3D"h=
ttps://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea=
57ee792&id=3Df3967aa87a&e=3D006462e992" style=3D"mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #08=
4c61;font-weight: normal;text-decoration: underline;">ALS News Today</a>.<=
/p></span>
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</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnButtonBlock" style=3D"min-width: 100%;border-collapse: co=
llapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 1=
00%;-webkit-text-size-adjust: 100%;">
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                <table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" cl=
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rtant;border-radius: 43px;background-color: #FDBA53;mso-table-lspace: 0pt;=
mso-table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust:=
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                            <td align=3D"center" valign=3D"middle" class=
=3D"mcnButtonContent" style=3D"font-family: &quot;Helvetica Neue&quot;=2C=
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;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-siz=
e-adjust: 100%;">
                                <a class=3D"mcnButton " title=3D"Continue=
 Reading" href=3D"https://alsnewstoday.us5.list-manage.com/track/click?u=
=3D52c64784d386bd00ea57ee792&id=3D44359553fe&e=3D006462e992" target=3D"_b=
lank" style=3D"font-weight: bold;letter-spacing: normal;line-height: 100%;=
text-align: center;text-decoration: none;color: #084C61;mso-line-height-ru=
le: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;disp=
lay: block;">Continue Reading</a>
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</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
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t-text-size-adjust: 100%;">
              =09<!--[if mso]>
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                <table align=3D"left" border=3D"0" cellpadding=3D"0" cells=
pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
                    <tbody><tr>

                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding: 0px 18px 9px;text-align: left;mso-line-height-rule: exactly;-=
ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;word-break: break=
-word;color: #212121;font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C Verdana=2C sans-serif;font-size: 15px;line-height: 150%;">



<h2 class=3D"mc-toc-title" style=3D"display: block;margin: 0;padding: 0;co=
lor: #212121;font-family: 'Merriweather'=2C Georgia=2C 'Times New Roman'=
=2C serif;font-size: 17px;font-style: normal;font-weight: bold;line-height=
: 125%;letter-spacing: normal;text-align: left;"><a href=3D"https://alsnew=
stoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D=
d08abc0bb8&e=3D006462e992" target=3D"_blank" style=3D"mso-line-height-rul=
e: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color=
: #084c61;font-weight: normal;text-decoration: underline;">What my journal=
s reveal about my journey as an ALS caregiver</a></h2>
<span style=3D"color:#033443"><em>By Kristin Neva on </em></span><em>01/15=
/2026</em><br>
<span style=3D"color:#212121"><a href=3D"https://alsnewstoday.us5.list-man=
age.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D2b6dc721ae&e=3D006462e992" title=3D"What my journals reveal about my journey as an ALS careg=
iver" rel=3D"nofollow" style=3D"mso-line-height-rule: exactly;-ms-text-siz=
e-adjust: 100%;-webkit-text-size-adjust: 100%;color: #084c61;font-weight:=
 normal;text-decoration: underline;"><img width=3D"800" src=3D"https://als=
newstoday.com/wp-content/uploads/2020/09/kristinneva_joyfulsorrow-1024x384=
=2Ejpg" class=3D"webfeedsFeaturedVisual wp-post-image mcRssImage" alt=3D"Mai=
n graphic for &quot;Joyful Sorrow&quot; column by Kristin Neva" style=3D"m=
ax-width: 100%;width: 100%;padding-bottom: 0;display: inline;vertical-alig=
n: bottom;border: 0;height: auto;outline: none;text-decoration: none;-ms-i=
nterpolation-mode: bicubic;" link_thumbnail=3D"1" decoding=3D"async" loadi=
ng=3D"lazy" srcset=3D"https://alsnewstoday.com/wp-content/uploads/2020/09/=
kristinneva_joyfulsorrow-1024x384.jpg 1024w=2C https://alsnewstoday.com/wp=
-content/uploads/2020/09/kristinneva_joyfulsorrow-300x113.jpg 300w=2C http=
s://alsnewstoday.com/wp-content/uploads/2020/09/kristinneva_joyfulsorrow-7=
68x288.jpg 768w=2C https://alsnewstoday.com/wp-content/uploads/2020/09/kri=
stinneva_joyfulsorrow-1200x450.jpg 1200w=2C https://alsnewstoday.com/wp-co=
ntent/uploads/2020/09/kristinneva_joyfulsorrow.jpg 1400w" sizes=3D"(max-wi=
dth: 800px) 100vw=2C 800px" data-wp-pid=3D"37676" border=3D"0"></a><p styl=
e=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;color: #212121;font-family: '=
Helvetica Neue'=2C Helvetica=2C Arial=2C Verdana=2C sans-serif;font-size:=
 15px;line-height: 150%;text-align: left;">Every step of an ALS journey is=
 difficult=2C but somehow we=E2=80=99re wired with the ability to forget m=
uch of the pain and remember the good. I wrote last week about our current=
 challenge of finding nighttime caregivers. After getting all of the shift=
s covered=2C one of our caregivers who had picked up an additional night [=
&#8230;]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #212121;font-fa=
mily: 'Helvetica Neue'=2C Helvetica=2C Arial=2C Verdana=2C sans-serif;font=
-size: 15px;line-height: 150%;text-align: left;">The post <a href=3D"https=
://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee=
792&id=3Ddaaf44f4b1&e=3D006462e992" style=3D"mso-line-height-rule: exactl=
y;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #084c61=
;font-weight: normal;text-decoration: underline;">What my journals reveal=
 about my journey as an ALS caregiver</a> appeared first on <a href=3D"htt=
ps://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57=
ee792&id=3Dcb7f8d0a56&e=3D006462e992" style=3D"mso-line-height-rule: exac=
tly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #084c=
61;font-weight: normal;text-decoration: underline;">ALS News Today</a>.</p=
></span>
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rtant;border-radius: 43px;background-color: #FDBA53;mso-table-lspace: 0pt;=
mso-table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust:=
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                            <td align=3D"center" valign=3D"middle" class=
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;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-siz=
e-adjust: 100%;">
                                <a class=3D"mcnButton " title=3D"Continue=
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lank" style=3D"font-weight: bold;letter-spacing: normal;line-height: 100%;=
text-align: center;text-decoration: none;color: #084C61;mso-line-height-ru=
le: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;disp=
lay: block;">Continue Reading</a>
                            </td>
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pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
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                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding: 0px 18px 9px;text-align: left;mso-line-height-rule: exactly;-=
ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;word-break: break=
-word;color: #212121;font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C Verdana=2C sans-serif;font-size: 15px;line-height: 150%;">



<h2 class=3D"mc-toc-title" style=3D"display: block;margin: 0;padding: 0;co=
lor: #212121;font-family: 'Merriweather'=2C Georgia=2C 'Times New Roman'=
=2C serif;font-size: 17px;font-style: normal;font-weight: bold;line-height=
: 125%;letter-spacing: normal;text-align: left;"><a href=3D"https://alsnew=
stoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D=
2a49492065&e=3D006462e992" target=3D"_blank" style=3D"mso-line-height-rul=
e: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color=
: #084c61;font-weight: normal;text-decoration: underline;">Clene=2C FDA to=
 discuss survival data and approval path for CNM-Au8</a></h2>
<span style=3D"color:#033443"><em>By Marisa Wexler=2C MS on </em></span><e=
m>01/15/2026</em><br>
<span style=3D"color:#212121"><a href=3D"https://alsnewstoday.us5.list-man=
age.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3Dcba29108a5&e=3D006462e992" title=3D"Clene=2C FDA to discuss survival data and approval path=
 for CNM-Au8" rel=3D"nofollow" style=3D"mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #084c61;font-=
weight: normal;text-decoration: underline;"><img width=3D"700" src=3D"http=
s://alsnewstoday.com/wp-content/uploads/2024/06/collaboration-chat.png" cl=
ass=3D"webfeedsFeaturedVisual wp-post-image mcRssImage" alt=3D"Speech bubb=
les show a thumbs-up sign and pages of documents as two people talk during=
 a meeting." style=3D"max-width: 100%;width: 100%;padding-bottom: 0;displa=
y: inline;vertical-align: bottom;border: 0;height: auto;outline: none;text=
-decoration: none;-ms-interpolation-mode: bicubic;" link_thumbnail=3D"1" d=
ecoding=3D"async" loading=3D"lazy" srcset=3D"https://alsnewstoday.com/wp-c=
ontent/uploads/2024/06/collaboration-chat.png 700w=2C https://alsnewstoday=
=2Ecom/wp-content/uploads/2024/06/collaboration-chat-380x190.png 380w" sizes=
=3D"(max-width: 700px) 100vw=2C 700px" data-wp-pid=3D"92551" border=3D"0">=
</a><p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-m=
s-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #212121;fon=
t-family: 'Helvetica Neue'=2C Helvetica=2C Arial=2C Verdana=2C sans-serif;=
font-size: 15px;line-height: 150%;text-align: left;">Clene is scheduled to=
 meet with the U.S. Food and Drug Administration (FDA) in the coming month=
s to discuss new data and a potential path toward accelerated approval for=
 CNM-Au8=2C an oral therapy being developed for amyotrophic lateral sclero=
sis (ALS). The company plans to argue that the treatment&#8217;s ability t=
o lower key markers of nerve [&#8230;]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #212121;font-fa=
mily: 'Helvetica Neue'=2C Helvetica=2C Arial=2C Verdana=2C sans-serif;font=
-size: 15px;line-height: 150%;text-align: left;">The post <a href=3D"https=
://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee=
792&id=3D691f16ae52&e=3D006462e992" style=3D"mso-line-height-rule: exactl=
y;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #084c61=
;font-weight: normal;text-decoration: underline;">Clene=2C FDA to discuss=
 survival data and approval path for CNM-Au8</a> appeared first on <a href=
=3D"https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386b=
d00ea57ee792&id=3D9afc2d6c7f&e=3D006462e992" style=3D"mso-line-height-rul=
e: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color=
: #084c61;font-weight: normal;text-decoration: underline;">ALS News Today<=
/a>.</p></span>
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lank" style=3D"font-weight: bold;letter-spacing: normal;line-height: 100%;=
text-align: center;text-decoration: none;color: #084C61;mso-line-height-ru=
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lay: block;">Continue Reading</a>
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<h3 class=3D"null" style=3D"display: block;margin: 0;padding: 0;color: #21=
2121;font-family: 'Merriweather'=2C Georgia=2C 'Times New Roman'=2C serif;=
font-size: 17px;font-style: normal;font-weight: bold;line-height: 125%;let=
ter-spacing: normal;text-align: left;">More Recent Articles:</h3>
<a rel=3D"nofollow" target=3D"_blank" href=3D"https://alsnewstoday.us5.lis=
t-manage.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3Db2625e747b&e=
=3D006462e992" class=3D"rss-recent" style=3D"mso-line-height-rule: exactl=
y;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #084c61=
;font-weight: normal;text-decoration: underline;">Managing decision-making=
 fatigue with my 'two drawers' method</a><br><a rel=3D"nofollow" target=3D=
"_blank" href=3D"https://alsnewstoday.us5.list-manage.com/track/click?u=3D=
52c64784d386bd00ea57ee792&id=3D66b9f63a3b&e=3D006462e992" class=3D"rss-re=
cent" style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-w=
ebkit-text-size-adjust: 100%;color: #084c61;font-weight: normal;text-decor=
ation: underline;">First human trial begins in Europe for ALS=2C Parkinson=
's drug NRG5051</a><br><a rel=3D"nofollow" target=3D"_blank" href=3D"https=
://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee=
792&id=3D453fcf0e1c&e=3D006462e992" class=3D"rss-recent" style=3D"mso-lin=
e-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust=
: 100%;color: #084c61;font-weight: normal;text-decoration: underline;">ALS=
 gene therapy targeting TDP-43 protein put on FDA fast track</a><br><a rel=
=3D"nofollow" target=3D"_blank" href=3D"https://alsnewstoday.us5.list-mana=
ge.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3Dfffb098979&e=3D006462e992" class=3D"rss-recent" style=3D"mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #084c61;font-we=
ight: normal;text-decoration: underline;">ALS Association fears 'instabili=
ty' with removal of NINDS director</a><br><a rel=3D"nofollow" target=3D"_b=
lank" href=3D"https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c=
64784d386bd00ea57ee792&id=3D942c0b8b35&e=3D006462e992" class=3D"rss-recen=
t" style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webk=
it-text-size-adjust: 100%;color: #084c61;font-weight: normal;text-decorati=
on: underline;">Aperture advances RNA-targeting treatment for ALS</a>
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st: 100%;">
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tent" style=3D"padding: 18px;color: #FFFFFF;font-family: Helvetica;font-si=
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tly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;word-break:=
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lign: center;display: block;margin: 0;padding: 0;color: #212121;font-famil=
y: 'Merriweather'=2C Georgia=2C 'Times New Roman'=2C serif;font-size: 17px=
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rmal;"><span style=3D"color:#FFFFFF">Discuss these topics and much more on=
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                                                    <td valign=3D"top" sty=
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y;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;" class=3D"mcn=
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                                                                         =
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                                                <tbody><tr>
                                                    <td valign=3D"top" sty=
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padding-bottom: 5px;padding-left: 9px;mso-line-height-rule: exactly;-ms-te=
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ft;">
                                                                        <t=
body><tr>

                                                                         =
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                                        <!--[if mso]>
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                                        <![endif]-->

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                                            <table align=3D"left" border=
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ize-adjust: 100%;-webkit-text-size-adjust: 100%;float: left;">
                                                <tbody><tr>
                                                    <td valign=3D"top" sty=
le=3D"padding-right: 0;padding-bottom: 9px;mso-line-height-rule: exactly;-=
ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;" class=3D"mcnFol=
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>
                                                            <tbody><tr>
                                                                <td align=
=3D"left" valign=3D"middle" style=3D"padding-top: 5px;padding-right: 10px;=
padding-bottom: 5px;padding-left: 9px;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
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ft;">
                                                                        <t=
body><tr>

                                                                         =
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lowIconContent" style=3D"mso-line-height-rule: exactly;-ms-text-size-adjus=
t: 100%;-webkit-text-size-adjust: 100%;">
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</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
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=09<![endif]-->
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