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** ALS-causing gene mutations disrupt key protein machinery: Study (https:=
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Mutations in the NEK1 gene =E2=80=94 a major genetic cause of amyotrophic=
 lateral sclerosis (ALS) =E2=80=94 can disrupt the molecular machinery tha=
t cells normally rely on to make new proteins=2C according to a new study.=
 The results shed new light on the molecular mechanisms by which certain m=
utations can contribute to ALS. The study=2C =E2=80=9CNuclear condensates=
 [=E2=80=A6]

The post ALS-causing gene mutations disrupt key protein machinery: Study (=
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** Higher levels of certain fat molecules in the body may increase ALS ris=
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Abnormal levels of certain fatty molecules in the body =E2=80=94 which are=
 broken down by metabolism to support daily functions =E2=80=94may increas=
e the risk of amyotrophic lateral sclerosis (ALS)=2C according to a new st=
udy. The research=2C which was based on genetic data to reduce the influen=
ce of external factors=2C =E2=80=9Cprovides genetic evidence supporting po=
tential associations [=E2=80=A6]

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** ALS limits the shared experiences my husband and I can enjoy (https://u=
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My brother and his family visited from out of town for a few days=2C so I=
 planned a couple activities away from home and hired a caregiver for my h=
usband=2C Todd=2C who has ALS and is paralyzed. Now that his neck is very=
 weak and he needs noninvasive ventilation=2C he doesn=E2=80=99t find it c=
omfortable to [=E2=80=A6]

The post ALS limits the shared experiences my husband and I can enjoy (htt=
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0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
                    <tbody><tr>

                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding: 0px 18px 9px;color: #222222;font-family: Arial=2C &quot;Helve=
tica Neue&quot;=2C Helvetica=2C sans-serif;font-size: 16px;font-weight: no=
rmal;text-align: left;mso-line-height-rule: exactly;-ms-text-size-adjust:=
 100%;-webkit-text-size-adjust: 100%;word-break: break-word;line-height: 1=
50%;">

                            <!-- Section Label -->
<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
margin-bottom: 16px;border-collapse: collapse;mso-table-lspace: 0pt;mso-ta=
ble-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;=
" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"background-color: #1754ff;border-radius: 2px;mso-lin=
e-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust=
: 100%;" width=3D"4">&nbsp;</td>
=09=09=09<td style=3D"padding-left: 8px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<p style=3D"margin: 0px;font-family: &quot;Helvetica Neue&quot;=
=2C Helvetica=2C Arial=2C sans-serif;font-weight: 700;text-transform: uppe=
rcase;letter-spacing: 1px;padding: 0;mso-line-height-rule: exactly;-ms-tex=
t-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #222222;font-siz=
e: 18px;line-height: 150%;text-align: left;"><font color=3D"#000000"><span=
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an></font></p>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>
<!-- Intro Text --><!-- Feed Block --><br>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/ekj9h_yA=
Vt7?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3Di7-WeZ8pOZtil8MLmbEKjAaeakqOMGcxWRutsqvulq4O2bO1RigbIbvyIvrH3WMcPMB-zNayJK4Pp_WW7979m1fGBA=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">ALS-causing gene mutations disrupt key prote=
in machinery: Study</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/10pkuTOX=
21O?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DAxJpMmoGwLYkpeAYHFSV0fNBNrHFIBOmObZt6A_lrz3Q7Vt6z0_J9PB5NarL_tZQHxECXaRIOSM_TiFPKfIYly-7BA=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">Higher levels of certain fat molecules in th=
e body may increase ALS risk</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/aNgAohHV=
t_W?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3Dsln-6loZHFbreIOoRo0hVj6Ga6jByNlctnqUfGs_683sAffm5u4yXv7OWnzwFkRcGIPwbRHBrY7QcorglfIvqMi7MQ=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">Study finds 4-month diagnostic gap between k=
ey ALS types</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

                        </td>
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=09=09=09=09<!--[if mso]>
=09=09=09=09</td>
=09=09=09=09<![endif]-->

=09=09=09=09<!--[if mso]>
=09=09=09=09</tr>
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=09=09=09=09<![endif]-->
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g=3D"0" cellspacing=3D"0" width=3D"100%" style=3D"min-width: 100%;border-t=
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table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100=
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t-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
                            <span></span>
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g-top: 9px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webki=
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              =09<!--[if mso]>
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=09=09=09=09<tr>
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=09=09=09
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=09=09=09=09<td valign=3D"top" width=3D"NaN" style=3D"width:NaNpx;">
=09=09=09=09<![endif]-->
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pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
                    <tbody><tr>

                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding: 0px 18px 9px;color: #222222;font-family: Arial=2C &quot;Helve=
tica Neue&quot;=2C Helvetica=2C sans-serif;font-size: 16px;font-weight: no=
rmal;text-align: left;mso-line-height-rule: exactly;-ms-text-size-adjust:=
 100%;-webkit-text-size-adjust: 100%;word-break: break-word;line-height: 1=
50%;">

                            <!-- Section Label -->
<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
margin-bottom: 16px;border-collapse: collapse;mso-table-lspace: 0pt;mso-ta=
ble-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;=
" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"background-color: #05D3AB;border-radius: 2px;mso-lin=
e-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust=
: 100%;" width=3D"4">&nbsp;</td>
=09=09=09<td style=3D"padding-left: 8px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<p style=3D"margin: 0px;font-family: &quot;Helvetica Neue&quot;=
=2C Helvetica=2C Arial=2C sans-serif;font-weight: 700;text-transform: uppe=
rcase;letter-spacing: 1px;padding: 0;mso-line-height-rule: exactly;-ms-tex=
t-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #222222;font-siz=
e: 18px;line-height: 150%;text-align: left;"><font color=3D"#000000"><span=
 style=3D"font-size:15px">Community Voices</span></font></p>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>
<!-- Intro Text --><!-- Feed Block --><br>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/TEebllVS=
l2q?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3Da5AKrpueyeSxFHIUOY1SqS97idCKls7zKQkKajz-spEktkzpfxhM1YlFlyTzO1nGjQcCzNm6e0KeUH0RfXa1yWW_cQ=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">ALS limits the shared experiences my husband=
 and I can enjoy</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/8BJdMK1A=
N4N?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D0V7IAZB8N1VPHN43zs9PSDBWCcAeLGl-9ppim7vZ5OCZsMJ6fAhDZQgZtjXrqlMgt_B6RVLIb0EmZAZ0Ux-6KMa4GA=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">Knowing my body isn=E2=80=99t my enemy helps=
 me be at peace with ALS symptoms</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/1BKTnFOm=
nk2?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DPalDq6xP3dyBKkgHDTDOGU_ObC6Wny1BjtIl2fNodSCpzO4jXTxqGGoSKs8sHduMQ8tfF5Snv4Z4n_nua_6q1r2UrA=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">Guest Voice: The collateral damage of ALS</a=
></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

                        </td>
                    </tr>
                </tbody></table>
=09=09=09=09<!--[if mso]>
=09=09=09=09</td>
=09=09=09=09<![endif]-->

=09=09=09=09<!--[if mso]>
=09=09=09=09</tr>
=09=09=09=09</table>
=09=09=09=09<![endif]-->
            </td>
        </tr>
    </tbody>
</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnDividerBlock" style=3D"min-width: 100%;border-collapse: c=
ollapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust:=
 100%;-webkit-text-size-adjust: 100%;table-layout: fixed !important;">
    <tbody class=3D"mcnDividerBlockOuter">
        <tr>
            <td class=3D"mcnDividerBlockInner" style=3D"min-width: 100%;pa=
dding: 5px 18px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-=
webkit-text-size-adjust: 100%;">
                <table class=3D"mcnDividerContent" border=3D"0" cellpaddin=
g=3D"0" cellspacing=3D"0" width=3D"100%" style=3D"min-width: 100%;border-t=
op: 2px solid #EAEAEA;border-collapse: collapse;mso-table-lspace: 0pt;mso-=
table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100=
%;">
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                        <td style=3D"mso-line-height-rule: exactly;-ms-tex=
t-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
                            <span></span>
                        </td>
                    </tr>
                </tbody></table>
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</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
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%;-webkit-text-size-adjust: 100%;">
    <tbody class=3D"mcnTextBlockOuter">
        <tr>
            <td valign=3D"top" class=3D"mcnTextBlockInner" style=3D"paddin=
g-top: 9px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webki=
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              =09<!--[if mso]>
=09=09=09=09<table align=3D"left" border=3D"0" cellspacing=3D"0" cellpaddi=
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=09=09=09=09<tr>
=09=09=09=09<![endif]-->
=09=09=09
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=09=09=09=09<td valign=3D"top" width=3D"NaN" style=3D"width:NaNpx;">
=09=09=09=09<![endif]-->
                <table align=3D"left" border=3D"0" cellpadding=3D"0" cells=
pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
                    <tbody><tr>

                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding: 0px 18px 9px;color: #222222;font-family: Arial=2C &quot;Helve=
tica Neue&quot;=2C Helvetica=2C sans-serif;font-size: 16px;font-weight: no=
rmal;text-align: left;mso-line-height-rule: exactly;-ms-text-size-adjust:=
 100%;-webkit-text-size-adjust: 100%;word-break: break-word;line-height: 1=
50%;">

                            <!-- Section Label -->
<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
margin-bottom: 16px;border-collapse: collapse;mso-table-lspace: 0pt;mso-ta=
ble-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;=
" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"background-color: #1754ff;border-radius: 2px;mso-lin=
e-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust=
: 100%;" width=3D"4">&nbsp;</td>
=09=09=09<td style=3D"padding-left: 8px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<p style=3D"margin: 0px;font-family: &quot;Helvetica Neue&quot;=
=2C Helvetica=2C Arial=2C sans-serif;font-weight: 700;text-transform: uppe=
rcase;letter-spacing: 1px;padding: 0;mso-line-height-rule: exactly;-ms-tex=
t-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #222222;font-siz=
e: 18px;line-height: 150%;text-align: left;"><font color=3D"#000000"><span=
 style=3D"font-size:15px">FORUMs CONVERSATIONs</span></font></p>
=09=09=09</td>
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=09</tbody>
</table>
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<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
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qYK?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D0hCSPUrAYYIknlfT8MG15guHgrIjya3MUnIIavtnjldnEQFxmY88ep8lJVvfELoTxMNwZqJahF53AznKoM5XQrhH3Q=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">How do you manage the summer heat with ALS?<=
/a></h3>
=09=09=09</td>
=09=09</tr>
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background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
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=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
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C5i?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DGYJTLR0IGLeTXSNXbo0RJeYCCj-AhDFqq5TxYeEuETOJzjXbJ57P0bhN4CFyWf9XYuB4faMulRnk1TY03GvgklF-qg=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
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t: normal;" target=3D"_blank">Would you try out this robotic exoskeleton?<=
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=09=09=09</td>
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ble-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;=
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=09=09=09<td style=3D"background-color: #05D3AB;border-radius: 2px;mso-lin=
e-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust=
: 100%;" width=3D"4">&nbsp;</td>
=09=09=09<td style=3D"padding-left: 8px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<p style=3D"margin: 0px;font-family: &quot;Helvetica Neue&quot;=
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rcase;letter-spacing: 1px;padding: 0;mso-line-height-rule: exactly;-ms-tex=
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e: 16px;line-height: 150%;text-align: left;"><font color=3D"#000000"><span=
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<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
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=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
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t: normal;" target=3D"_blank">Therapeutic synergy: Benefits of a multiface=
ted ALS treatment strategy</a></h3>
=09=09=09</td>
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=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
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=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
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size-adjust: 100%;word-break: break-word;color: #202020;font-family: Helve=
tica;font-size: 16px;line-height: 150%;text-align: left;">


<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #ffffff;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
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ld) -->
=09=09=09<h2 style=3D"margin: 0 0 12px 0;font-family: 'Helvetica Neue'=2C=
 Helvetica=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color:=
 #000000;line-height: 1.3;display: block;padding: 0;font-style: normal;let=
ter-spacing: normal;text-align: left;"><a href=3D"https://us.list-manage.c=
om/kG6Hwlh0jss?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3Dt4UQDzIb_haIS2nUHECaFKeWbtiUbrUjjJaBw4BJoS7nLChkYriHY7ZqVgU9ZOAY1uyNratzBK5lJvHBnyx9nhBI_w=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-heig=
ht-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%=
;font-weight: normal;"><strong>ALS-causing gene mutations disrupt key prot=
ein machinery: Study</strong> </a></h2>
=09=09=09<!-- Article Content Preview (Black=2C 16px) -->

=09=09=09<div style=3D"font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C sans-serif; font-size: 14px; color: #000000; line-height: 1.6; margin:=
0 0 16px 0;"><a href=3D"https://us.list-manage.com/kc2DSHPkf_s?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DrhF7WU-qZD_cSnw6lq538HLKLmR3XtbM-GblERtRT93L6ascr-SwXYPpySMp" title=3D"AL=
S-causing gene mutations disrupt key protein machinery: Study" rel=3D"nofo=
llow" style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-w=
ebkit-text-size-adjust: 100%;color: #1e2559;font-weight: normal;text-decor=
ation: underline;"><img width=3D"700" src=3D"https://alsnewstoday.com/wp-c=
ontent/uploads/2022/07/DNA2.png" class=3D"webfeedsFeaturedVisual wp-post-i=
mage mcRssImage" alt=3D"A close-up view of a DNA strand highlights its lad=
der-like structure." style=3D"max-width: 100%;width: 100%;padding-bottom:=
 0;display: inline;vertical-align: bottom;border: 0;height: auto;outline:=
 none;text-decoration: none;-ms-interpolation-mode: bicubic;" link_thumbna=
il=3D"1" decoding=3D"async" loading=3D"lazy" srcset=3D"https://alsnewstoda=
y.com/wp-content/uploads/2022/07/DNA2.png 700w=2C https://alsnewstoday.com=
/wp-content/uploads/2022/07/DNA2-380x190.png 380w" sizes=3D"(max-width: 70=
0px) 100vw=2C 700px" border=3D"0"></a><p style=3D"margin: 10px 0;padding:=
 0;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-s=
ize-adjust: 100%;color: #202020;font-family: Helvetica;font-size: 16px;lin=
e-height: 150%;text-align: left;">Mutations in the=C2=A0NEK1 gene =E2=80=
=94 a major genetic cause of amyotrophic lateral sclerosis (ALS) =E2=80=94=
 can disrupt the molecular machinery that cells normally rely on to make n=
ew proteins=2C according to a new study. The results shed new light on the=
 molecular mechanisms by which certain mutations can contribute to ALS. Th=
e study=2C =E2=80=9CNuclear condensates [&#8230;]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-fa=
mily: Helvetica;font-size: 16px;line-height: 150%;text-align: left;">The p=
ost <a href=3D"https://us.list-manage.com/UAURyac1RPe?e=3D006462e992&c2id=
=3D6d8df1454ee901f23d2c8d3973c45e87&m=3Da3ykLjlEwlFqJ08MKLf_0Tt6V_rSITXnPTQGVxfJj5bawoI9bDXdwpFaiTgJ" style=3D"mso-line-he=
ight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 10=
0%;color: #1e2559;font-weight: normal;text-decoration: underline;">ALS-cau=
sing gene mutations disrupt key protein machinery: Study</a> appeared firs=
t on <a href=3D"https://us.list-manage.com/4DSpKiolQOw?e=3D006462e992&c2i=
d=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DWWaruGvzX2WrUh6e7zk3U4fPcXZSSAUAaMtPyRHSxL7VnwuS-YrilOC6E65P" style=3D"mso-line-h=
eight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 1=
00%;color: #1e2559;font-weight: normal;text-decoration: underline;">ALS Ne=
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us.list-manage.com/2oUHMXbjzbT?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D4jU2HKrIvlma9agXcllDU39Z9QS7mCZqBPqYi7fFcrchI-VXC5y8-aF36N3cfs4uh_D5ElbsjD4pUkeLZlRbl8i7Dg=3D=3D" style=3D"display: inline-block;padding: 12p=
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text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">Continue Reading <=
/a></td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #ffffff;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;"><!-- Article Title (Bo=
ld) -->
=09=09=09<h2 style=3D"margin: 0 0 12px 0;font-family: 'Helvetica Neue'=2C=
 Helvetica=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color:=
 #000000;line-height: 1.3;display: block;padding: 0;font-style: normal;let=
ter-spacing: normal;text-align: left;"><a href=3D"https://us.list-manage.c=
om/AMmnumM5hVE?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DgoAROQMd1NdgZBKdwwqcliDOsdaKTJXwwpY8EiMd1p5u9tjvMFwKXvpda0DmmQ_2ubtVzJPdjfdYF-BxI1Jso5u6SQ=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-heig=
ht-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%=
;font-weight: normal;"><strong>Higher levels of certain fat molecules in t=
he body may increase ALS risk</strong> </a></h2>
=09=09=09<!-- Article Content Preview (Black=2C 16px) -->

=09=09=09<div style=3D"font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C sans-serif; font-size: 14px; color: #000000; line-height: 1.6; margin:=
0 0 16px 0;"><a href=3D"https://us.list-manage.com/WsQXryuMHzp?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DmdMvKfXcuTqkoXUO6XEbymtU7sSLTp6RbYxJb9O7CLI-ihDf5Jf22PGn0j83" title=3D"Hi=
gher levels of certain fat molecules in the body may increase ALS risk" re=
l=3D"nofollow" style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust=
: 100%;-webkit-text-size-adjust: 100%;color: #1e2559;font-weight: normal;t=
ext-decoration: underline;"><img width=3D"700" src=3D"https://alsnewstoday=
=2Ecom/wp-content/uploads/2022/07/DNA2.png" class=3D"webfeedsFeaturedVisual=
 wp-post-image mcRssImage" alt=3D"A close-up view of a DNA strand highligh=
ts its ladder-like structure." style=3D"max-width: 100%;width: 100%;paddin=
g-bottom: 0;display: inline;vertical-align: bottom;border: 0;height: auto;=
outline: none;text-decoration: none;-ms-interpolation-mode: bicubic;" link=
_thumbnail=3D"1" decoding=3D"async" loading=3D"lazy" srcset=3D"https://als=
newstoday.com/wp-content/uploads/2022/07/DNA2.png 700w=2C https://alsnewst=
oday.com/wp-content/uploads/2022/07/DNA2-380x190.png 380w" sizes=3D"(max-w=
idth: 700px) 100vw=2C 700px" border=3D"0"></a><p style=3D"margin: 10px 0;p=
adding: 0;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit=
-text-size-adjust: 100%;color: #202020;font-family: Helvetica;font-size: 1=
6px;line-height: 150%;text-align: left;">Abnormal levels of certain fatty=
 molecules in the body =E2=80=94 which are broken down by metabolism to su=
pport daily functions =E2=80=94may increase the risk of amyotrophic latera=
l sclerosis (ALS)=2C according to a new study. The research=2C which was b=
ased on genetic data to reduce the influence of external factors=2C &#8220=
;provides genetic evidence supporting potential associations [&#8230;]</p=
>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-fa=
mily: Helvetica;font-size: 16px;line-height: 150%;text-align: left;">The p=
ost <a href=3D"https://us.list-manage.com/19KxhzFFtEO?e=3D006462e992&c2id=
=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DHHTaZvyB-Ce-zqIprV__9LeGVIps6_1BPUuvcqg0gpT2pCTbRtVrdtA7Pic9" style=3D"mso-line-he=
ight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 10=
0%;color: #1e2559;font-weight: normal;text-decoration: underline;">Higher=
 levels of certain fat molecules in the body may increase ALS risk</a> app=
eared first on <a href=3D"https://us.list-manage.com/TvqwBCvyeGV?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DS-_088ALPfzp01E0o4N9JrU2qsvbq3qgA4gn6V4tsm7YX3aKUOvnjVoNvZxx" style=3D"=
mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size=
-adjust: 100%;color: #1e2559;font-weight: normal;text-decoration: underlin=
e;">ALS News Today</a>.</p></div>
=09=09=09<!-- Continue Reading Button (Filled Blue) --><a href=3D"https://=
us.list-manage.com/UeA0_6mIAJb?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DuRb57piEvbBKfCkb39o-MOHzQW5kYKu-Fgjv8WdlKtGOPNCON9GhufzPgXEUhGGdGvXm_koKkJstBR9RjUGExGIeng=3D=3D" style=3D"display: inline-block;padding: 12p=
x 24px;background-color: #1754FF;color: #ffffff;font-family: 'Helvetica Ne=
ue'=2C Helvetica=2C Arial=2C sans-serif;font-size: 14px;font-weight: 600;t=
ext-decoration: none;border-radius: 6px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">Continue Reading <=
/a></td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #ffffff;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;"><!-- Article Title (Bo=
ld) -->
=09=09=09<h2 style=3D"margin: 0 0 12px 0;font-family: 'Helvetica Neue'=2C=
 Helvetica=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color:=
 #000000;line-height: 1.3;display: block;padding: 0;font-style: normal;let=
ter-spacing: normal;text-align: left;"><a href=3D"https://us.list-manage.c=
om/OXyEV_BljyL?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D3q212-4Cq2Aqqdr4Pj0RzE6WdIwkaFjUCPJshxQQiXTRIB1UJGi53TnK-wAcP6e89Alh5pUExXr7DxH8asSjn5kJgg=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-heig=
ht-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%=
;font-weight: normal;"><strong>ALS limits the shared experiences my husban=
d and I can enjoy</strong> </a></h2>
=09=09=09<!-- Article Content Preview (Black=2C 16px) -->

=09=09=09<div style=3D"font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C sans-serif; font-size: 14px; color: #000000; line-height: 1.6; margin:=
0 0 16px 0;"><a href=3D"https://us.list-manage.com/Pm0B9ue9LJ4?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D_L0FRrYzCIZDonWZYm02ASTv2AjRE-77FQlZ5PmIeONQjYoJpb6JjJeMEXYo" title=3D"AL=
S limits the shared experiences my husband and I can enjoy" rel=3D"nofollo=
w" style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webk=
it-text-size-adjust: 100%;color: #1e2559;font-weight: normal;text-decorati=
on: underline;"><img width=3D"800" src=3D"https://alsnewstoday.com/wp-cont=
ent/uploads/2020/09/kristinneva_joyfulsorrow-1024x384.jpg" class=3D"webfee=
dsFeaturedVisual wp-post-image mcRssImage" alt=3D"Main graphic for &quot;J=
oyful Sorrow&quot; column by Kristin Neva." style=3D"max-width: 100%;width=
: 100%;padding-bottom: 0;display: inline;vertical-align: bottom;border: 0;=
height: auto;outline: none;text-decoration: none;-ms-interpolation-mode: b=
icubic;" link_thumbnail=3D"1" decoding=3D"async" loading=3D"lazy" srcset=
=3D"https://alsnewstoday.com/wp-content/uploads/2020/09/kristinneva_joyful=
sorrow-1024x384.jpg 1024w=2C https://alsnewstoday.com/wp-content/uploads/2=
020/09/kristinneva_joyfulsorrow-300x113.jpg 300w=2C https://alsnewstoday.c=
om/wp-content/uploads/2020/09/kristinneva_joyfulsorrow-768x288.jpg 768w=2C=
 https://alsnewstoday.com/wp-content/uploads/2020/09/kristinneva_joyfulsor=
row-1200x450.jpg 1200w=2C https://alsnewstoday.com/wp-content/uploads/2020=
/09/kristinneva_joyfulsorrow.jpg 1400w" sizes=3D"(max-width: 800px) 100vw=
=2C 800px" border=3D"0"></a><p style=3D"margin: 10px 0;padding: 0;mso-line=
-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust:=
 100%;color: #202020;font-family: Helvetica;font-size: 16px;line-height: 1=
50%;text-align: left;">My brother and his family visited from out of town=
 for a few days=2C so I planned a couple activities away from home and hir=
ed a caregiver for my husband=2C Todd=2C who has ALS and is paralyzed. Now=
 that his neck is very weak and he needs noninvasive ventilation=2C he doe=
sn=E2=80=99t find it comfortable to [&#8230;]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-fa=
mily: Helvetica;font-size: 16px;line-height: 150%;text-align: left;">The p=
ost <a href=3D"https://us.list-manage.com/8giNoggbji3?e=3D006462e992&c2id=
=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DGKst_kxRb8W32Zgs52vfX19u3TeDr0pPMHaybKq6KD1KESyHru95eLa4kVtH" style=3D"mso-line-he=
ight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 10=
0%;color: #1e2559;font-weight: normal;text-decoration: underline;">ALS lim=
its the shared experiences my husband and I can enjoy</a> appeared first o=
n <a href=3D"https://us.list-manage.com/LItH3Bto4Ux?e=3D006462e992&c2id=
=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D5vPdjUthi2GLDP0re2u2A8cmZ0RIkKmvb956sv7Ods68yrfd9oulgWazO0U-" style=3D"mso-line-he=
ight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 10=
0%;color: #1e2559;font-weight: normal;text-decoration: underline;">ALS New=
s Today</a>.</p></div>
=09=09=09<!-- Continue Reading Button (Filled Blue) --><a href=3D"https://=
us.list-manage.com/XJvK2BzVN67?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D6WxJAa1G3AiwiiUFBpzYZc5o4NSIt0aTnoW3pUX2b3hAZQ7lRhIadHXeYt_A3vL7IqE5d0tfRKd-pk1LCBPTeAnfig=3D=3D" style=3D"display: inline-block;padding: 12p=
x 24px;background-color: #1754FF;color: #ffffff;font-family: 'Helvetica Ne=
ue'=2C Helvetica=2C Arial=2C sans-serif;font-size: 14px;font-weight: 600;t=
ext-decoration: none;border-radius: 6px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">Continue Reading <=
/a></td>
=09=09</tr>
=09</tbody>
</table>

                        </td>
                    </tr>
                </tbody></table>
=09=09=09=09<!--[if mso]>
=09=09=09=09</td>
=09=09=09=09<![endif]-->

=09=09=09=09<!--[if mso]>
=09=09=09=09</tr>
=09=09=09=09</table>
=09=09=09=09<![endif]-->
            </td>
        </tr>
    </tbody>
</table></td>
                            </tr>
                            <tr>
                                <td valign=3D"top" id=3D"templateColumns"=
 style=3D"background: #ffffff none no-repeat center/cover;mso-line-height-=
rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;ba=
ckground-color: #ffffff;background-image: none;background-repeat: no-repea=
t;background-position: center;background-size: cover;border-top: 0;border-=
bottom: 0;padding-top: 0;padding-bottom: 0;">
                                    <!--[if (gte mso 9)|(IE)]>
                                    <table align=3D"center" border=3D"0" c=
ellspacing=3D"0" cellpadding=3D"0" width=3D"600" style=3D"width:600px;">
                                    <tr>
                                    <td align=3D"center" valign=3D"top" wi=
dth=3D"300" style=3D"width:300px;">
                                    <![endif]-->
                                    <table align=3D"left" border=3D"0" cel=
lpadding=3D"0" cellspacing=3D"0" width=3D"300" class=3D"columnWrapper" sty=
le=3D"border-collapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0p=
t;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;float: left;">
                                        <tr>
                                            <td valign=3D"top" class=3D"co=
lumnContainer" style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust=
: 100%;-webkit-text-size-adjust: 100%;"></td>
                                        </tr>
                                    </table>
                                    <!--[if (gte mso 9)|(IE)]>
                                    </td>
                                    <td align=3D"center" valign=3D"top" wi=
dth=3D"300" style=3D"width:300px;">
                                    <![endif]-->
                                    <table align=3D"left" border=3D"0" cel=
lpadding=3D"0" cellspacing=3D"0" width=3D"300" class=3D"columnWrapper" sty=
le=3D"border-collapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0p=
t;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;float: left;">
                                        <tr>
                                            <td valign=3D"top" class=3D"co=
lumnContainer" style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust=
: 100%;-webkit-text-size-adjust: 100%;"></td>
                                        </tr>
                                    </table>
                                    <!--[if (gte mso 9)|(IE)]>
                                    </td>
                                    </tr>
                                    </table>
                                    <![endif]-->
                                </td>
                            </tr>
                            <tr>
                                <td valign=3D"top" id=3D"templateLowerBody=
" style=3D"background: #ffffff none no-repeat center/cover;mso-line-height=
-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;b=
ackground-color: #ffffff;background-image: none;background-repeat: no-repe=
at;background-position: center;background-size: cover;border-top: 0;border=
-bottom: 2px solid #ffffff;padding-top: 0;padding-bottom: 0px;"><table bor=
der=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"100%" class=3D"mcnD=
ividerBlock" style=3D"min-width: 100%;border-collapse: collapse;mso-table-=
lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;table-layout: fixed !important;">
    <tbody class=3D"mcnDividerBlockOuter">
        <tr>
            <td class=3D"mcnDividerBlockInner" style=3D"min-width: 100%;pa=
dding: 5px 18px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-=
webkit-text-size-adjust: 100%;">
                <table class=3D"mcnDividerContent" border=3D"0" cellpaddin=
g=3D"0" cellspacing=3D"0" width=3D"100%" style=3D"min-width: 100%;border-t=
op: 2px solid #EAEAEA;border-collapse: collapse;mso-table-lspace: 0pt;mso-=
table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100=
%;">
                    <tbody><tr>
                        <td style=3D"mso-line-height-rule: exactly;-ms-tex=
t-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
                            <span></span>
                        </td>
                    </tr>
                </tbody></table>
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                <td class=3D"mcnDividerBlockInner" style=3D"padding: 18px;=
">
                <hr class=3D"mcnDividerContent" style=3D"border-bottom-col=
or:none; border-left-color:none; border-right-color:none; border-bottom-wi=
dth:0; border-left-width:0; border-right-width:0; margin-top:0; margin-rig=
ht:0; margin-bottom:0; margin-left:0;" />
-->
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        </tr>
    </tbody>
</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnTextBlock" style=3D"min-width: 100%;border-collapse: coll=
apse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 100=
%;-webkit-text-size-adjust: 100%;">
    <tbody class=3D"mcnTextBlockOuter">
        <tr>
            <td valign=3D"top" class=3D"mcnTextBlockInner" style=3D"paddin=
g-top: 9px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webki=
t-text-size-adjust: 100%;">
              =09<!--[if mso]>
=09=09=09=09<table align=3D"left" border=3D"0" cellspacing=3D"0" cellpaddi=
ng=3D"0" width=3D"100%" style=3D"width:100%;">
=09=09=09=09<tr>
=09=09=09=09<![endif]-->
=09=09=09
=09=09=09=09<!--[if mso]>
=09=09=09=09<td valign=3D"top" width=3D"600" style=3D"width:600px;">
=09=09=09=09<![endif]-->
                <table align=3D"left" border=3D"0" cellpadding=3D"0" cells=
pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
                    <tbody><tr>

                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding-top: 0;padding-right: 18px;padding-bottom: 9px;padding-left: 1=
8px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;word-break: break-word;color: #222222;font-family: Helve=
tica;font-size: 16px;line-height: 200%;text-align: left;">

                            <div style=3D"text-align: center;"><span style=
=3D"font-size:14px"><em><strong>Follow us on social media for exclusive co=
ntent=2C and visit our website to learn about our Advocacy Partners: The A=
LS Association=2C Muscular Dystrophy Association=2C and The ALS Network</s=
trong></em></span></div>

                        </td>
                    </tr>
                </tbody></table>
=09=09=09=09<!--[if mso]>
=09=09=09=09</td>
=09=09=09=09<![endif]-->

=09=09=09=09<!--[if mso]>
=09=09=09=09</tr>
=09=09=09=09</table>
=09=09=09=09<![endif]-->
            </td>
        </tr>
    </tbody>
</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnFollowBlock" style=3D"min-width: 100%;border-collapse: co=
llapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 1=
00%;-webkit-text-size-adjust: 100%;">
    <tbody class=3D"mcnFollowBlockOuter">
        <tr>
            <td align=3D"center" valign=3D"top" style=3D"padding: 9px;mso-=
line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adj=
ust: 100%;" class=3D"mcnFollowBlockInner">
                <table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" wi=
dth=3D"100%" class=3D"mcnFollowContentContainer" style=3D"min-width: 100%;=
border-collapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
    <tbody><tr>
        <td align=3D"center" style=3D"padding-left: 9px;padding-right: 9px=
;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-siz=
e-adjust: 100%;">
            <table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" class=
=3D"mcnFollowContent" style=3D"border-collapse: collapse;mso-table-lspace:=
 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-ad=
just: 100%;">
                <tbody><tr>
                    <td align=3D"center" valign=3D"top" style=3D"padding-t=
op: 9px;padding-right: 9px;padding-left: 9px;mso-line-height-rule: exactly=
;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
                        <table align=3D"center" border=3D"0" cellpadding=
=3D"0" cellspacing=3D"0" style=3D"border-collapse: collapse;mso-table-lspa=
ce: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size=
-adjust: 100%;">
                            <tbody><tr>
                                <td align=3D"center" valign=3D"top" style=
=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;">
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