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a57ee792&id=3D4d158d56d6&e=3D006462e992


Latest ALS nEWS & CLINICAL INSIGHTS


Community Voices


FORUMs CONVERSATIONs



** Accessible travel granted my late husband normalcy=2C independence (htt=
ps://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57=
ee792&id=3Dbd167d10fc&e=3D006462e992)
------------------------------------------------------------
https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00e=
a57ee792&id=3D12891cd31e&e=3D006462e992

I=E2=80=99m writing this column from vacation in a place I once traveled w=
ith my late husband=2C Jeff=2C long before he was diagnosed with ALS in 20=
18. It was a dream trip of his=2C and we went together for his birthday mo=
re than a decade ago. On this trip=2C we traversed cobblestone streets=2C=
 walked the beach=2C [=E2=80=A6]

The post Accessible travel granted my late husband normalcy=2C independenc=
e (https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd=
00ea57ee792&id=3D695766e056&e=3D006462e992) appeared first on ALS Ne=
ws Today (https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c6478=
4d386bd00ea57ee792&id=3Df638bdd31b&e=3D006462e992) .
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=3D52c64784d386bd00ea57ee792&id=3D28da99c3c5&e=3D006462e992)


** Amylyx advancing ALS treatment in trial after early safety data is posi=
tive (https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d38=
6bd00ea57ee792&id=3D4c21594e54&e=3D006462e992)
------------------------------------------------------------
https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00e=
a57ee792&id=3D1f1009a497&e=3D006462e992

The lowest tested dose of Amylyx Pharmaceuticals=E2=80=98 treatment candid=
ate AMX0114 was found to be safe and well tolerated among people with amyo=
trophic lateral sclerosis (ALS) in an ongoing Phase 1 clinical trial. Biom=
arkers of nerve damage due to ALS remained relatively stable from the stud=
y=E2=80=99s start =E2=80=94 a result the trial investigators believe may c=
hange with [=E2=80=A6]

The post Amylyx advancing ALS treatment in trial after early safety data i=
s positive (https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64=
784d386bd00ea57ee792&id=3D6e74ac9661&e=3D006462e992) appeared first=
 on ALS News Today (https://alsnewstoday.us5.list-manage.com/track/click?u=
=3D52c64784d386bd00ea57ee792&id=3Daac81dd503&e=3D006462e992) .
Continue Reading (https://alsnewstoday.us5.list-manage.com/track/click?u=
=3D52c64784d386bd00ea57ee792&id=3D5b92f7f530&e=3D006462e992)


** Planting seeds of hope in life with ALS (https://alsnewstoday.us5.list-=
manage.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3Da139f54f24&e=3D006462e992)
------------------------------------------------------------
https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00e=
a57ee792&id=3D0d6978e915&e=3D006462e992

A couple months ago=2C I planted zinnia and strawflower seeds in two plast=
ic bins and set them in the sunlight under our patio window in my dining r=
oom. I=E2=80=99ve grown vegetables from seeds in the past=2C but never flo=
wers. Vegetables feel practical because food is necessary to sustain life=
=2C while growing flowers feels like a [=E2=80=A6]

The post Planting seeds of hope in life with ALS (https://alsnewstoday.us5=
=2Elist-manage.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D2d940715c1=
&e=3D006462e992) appeared first on ALS News Today (https://alsnewsto=
day.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D8d2=
a494e47&e=3D006462e992) .
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=3D52c64784d386bd00ea57ee792&id=3Df1fc02b2f8&e=3D006462e992)


** New European trial testing safety of ALS therapy targeting fat metaboli=
sm (https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386b=
d00ea57ee792&id=3D8b51339d24&e=3D006462e992)
------------------------------------------------------------
https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00e=
a57ee792&id=3D1ea3b82566&e=3D006462e992

The first patient has been dosed in a Phase 1/2 clinical trial evaluating=
 Leal Therapeutics=E2=80=98 LTX-002=2C an antisense oligonucleotide design=
ed to target abnormalities in fat metabolism that may contribute to amyotr=
ophic lateral sclerosis (ALS). The NeurALS trial (NCT07660614) is now recr=
uiting an estimated 56 adults with ALS at two sites in Europe=2C with plan=
s to add [=E2=80=A6]

The post New European trial testing safety of ALS therapy targeting fat me=
tabolism (https://alsnewstoday.us5.list-manage.com/track/click?u=3D52c6478=
4d386bd00ea57ee792&id=3D854c88eeca&e=3D006462e992) appeared first on=
 ALS News Today (https://alsnewstoday.us5.list-manage.com/track/click?u=3D=
52c64784d386bd00ea57ee792&id=3D7707a4bbf3&e=3D006462e992) .
Continue Reading (https://alsnewstoday.us5.list-manage.com/track/click?u=
=3D52c64784d386bd00ea57ee792&id=3Dc80fbe8230&e=3D006462e992)
Follow us on social media for exclusive content=2C and visit our website t=
o learn about our Advocacy Partners: The ALS Association=2C Muscular Dystr=
ophy Association=2C and The ALS Network
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=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://alsnewstoday.us5.list-manag=
e.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D832535f2df&e=3D006462e992" style=3D"text-decoration: none;color: #000000;mso-line-height-rule:=
 exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-we=
ight: normal;" target=3D"_blank">Amylyx advancing ALS treatment in trial a=
fter early safety data is positive</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://alsnewstoday.us5.list-manag=
e.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D5947348123&e=3D006462e992" style=3D"text-decoration: none;color: #000000;mso-line-height-rule:=
 exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-we=
ight: normal;" target=3D"_blank">New European trial testing safety of ALS=
 therapy targeting fat metabolism</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://alsnewstoday.us5.list-manag=
e.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3Dbf0e5552ef&e=3D006462e992" style=3D"text-decoration: none;color: #000000;mso-line-height-rule:=
 exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-we=
ight: normal;" target=3D"_blank">Nura raises $74M to support ALS trial=2C=
 new nerve-protecting therapy</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

                        </td>
                    </tr>
                </tbody></table>
=09=09=09=09<!--[if mso]>
=09=09=09=09</td>
=09=09=09=09<![endif]-->

=09=09=09=09<!--[if mso]>
=09=09=09=09</tr>
=09=09=09=09</table>
=09=09=09=09<![endif]-->
            </td>
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</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnDividerBlock" style=3D"min-width: 100%;border-collapse: c=
ollapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust:=
 100%;-webkit-text-size-adjust: 100%;table-layout: fixed !important;">
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        <tr>
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dding: 5px 18px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-=
webkit-text-size-adjust: 100%;">
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g=3D"0" cellspacing=3D"0" width=3D"100%" style=3D"min-width: 100%;border-t=
op: 2px solid #EAEAEA;border-collapse: collapse;mso-table-lspace: 0pt;mso-=
table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100=
%;">
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t-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
                            <span></span>
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<!--
                <td class=3D"mcnDividerBlockInner" style=3D"padding: 18px;=
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or:none; border-left-color:none; border-right-color:none; border-bottom-wi=
dth:0; border-left-width:0; border-right-width:0; margin-top:0; margin-rig=
ht:0; margin-bottom:0; margin-left:0;" />
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</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnTextBlock" style=3D"min-width: 100%;border-collapse: coll=
apse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 100=
%;-webkit-text-size-adjust: 100%;">
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        <tr>
            <td valign=3D"top" class=3D"mcnTextBlockInner" style=3D"paddin=
g-top: 9px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webki=
t-text-size-adjust: 100%;">
              =09<!--[if mso]>
=09=09=09=09<table align=3D"left" border=3D"0" cellspacing=3D"0" cellpaddi=
ng=3D"0" width=3D"100%" style=3D"width:100%;">
=09=09=09=09<tr>
=09=09=09=09<![endif]-->
=09=09=09
=09=09=09=09<!--[if mso]>
=09=09=09=09<td valign=3D"top" width=3D"NaN" style=3D"width:NaNpx;">
=09=09=09=09<![endif]-->
                <table align=3D"left" border=3D"0" cellpadding=3D"0" cells=
pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
                    <tbody><tr>

                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding: 0px 18px 9px;color: #222222;font-family: Arial=2C &quot;Helve=
tica Neue&quot;=2C Helvetica=2C sans-serif;font-size: 16px;font-weight: no=
rmal;text-align: left;mso-line-height-rule: exactly;-ms-text-size-adjust:=
 100%;-webkit-text-size-adjust: 100%;word-break: break-word;line-height: 1=
50%;">

                            <!-- Section Label -->
<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
margin-bottom: 16px;border-collapse: collapse;mso-table-lspace: 0pt;mso-ta=
ble-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;=
" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"background-color: #05D3AB;border-radius: 2px;mso-lin=
e-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust=
: 100%;" width=3D"4">&nbsp;</td>
=09=09=09<td style=3D"padding-left: 8px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<p style=3D"margin: 0px;font-family: &quot;Helvetica Neue&quot;=
=2C Helvetica=2C Arial=2C sans-serif;font-weight: 700;text-transform: uppe=
rcase;letter-spacing: 1px;padding: 0;mso-line-height-rule: exactly;-ms-tex=
t-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #222222;font-siz=
e: 18px;line-height: 150%;text-align: left;"><font color=3D"#000000"><span=
 style=3D"font-size:15px">Community Voices</span></font></p>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>
<!-- Intro Text --><!-- Feed Block --><br>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://alsnewstoday.us5.list-manag=
e.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D0dde39b740&e=3D006462e992" style=3D"text-decoration: none;color: #000000;mso-line-height-rule:=
 exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-we=
ight: normal;" target=3D"_blank">Accessible travel granted my late husband=
 normalcy=2C independence</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://alsnewstoday.us5.list-manag=
e.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D850352cc6c&e=3D006462e992" style=3D"text-decoration: none;color: #000000;mso-line-height-rule:=
 exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-we=
ight: normal;" target=3D"_blank">Planting seeds of hope in life with ALS</=
a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://alsnewstoday.us5.list-manag=
e.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D6a3a2d4074&e=3D006462e992" style=3D"text-decoration: none;color: #000000;mso-line-height-rule:=
 exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-we=
ight: normal;" target=3D"_blank">This ALS caregiver is learning to hit the=
 pause button</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

                        </td>
                    </tr>
                </tbody></table>
=09=09=09=09<!--[if mso]>
=09=09=09=09</td>
=09=09=09=09<![endif]-->

=09=09=09=09<!--[if mso]>
=09=09=09=09</tr>
=09=09=09=09</table>
=09=09=09=09<![endif]-->
            </td>
        </tr>
    </tbody>
</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnDividerBlock" style=3D"min-width: 100%;border-collapse: c=
ollapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust:=
 100%;-webkit-text-size-adjust: 100%;table-layout: fixed !important;">
    <tbody class=3D"mcnDividerBlockOuter">
        <tr>
            <td class=3D"mcnDividerBlockInner" style=3D"min-width: 100%;pa=
dding: 5px 18px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-=
webkit-text-size-adjust: 100%;">
                <table class=3D"mcnDividerContent" border=3D"0" cellpaddin=
g=3D"0" cellspacing=3D"0" width=3D"100%" style=3D"min-width: 100%;border-t=
op: 2px solid #EAEAEA;border-collapse: collapse;mso-table-lspace: 0pt;mso-=
table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100=
%;">
                    <tbody><tr>
                        <td style=3D"mso-line-height-rule: exactly;-ms-tex=
t-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
                            <span></span>
                        </td>
                    </tr>
                </tbody></table>
<!--
                <td class=3D"mcnDividerBlockInner" style=3D"padding: 18px;=
">
                <hr class=3D"mcnDividerContent" style=3D"border-bottom-col=
or:none; border-left-color:none; border-right-color:none; border-bottom-wi=
dth:0; border-left-width:0; border-right-width:0; margin-top:0; margin-rig=
ht:0; margin-bottom:0; margin-left:0;" />
-->
            </td>
        </tr>
    </tbody>
</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnTextBlock" style=3D"min-width: 100%;border-collapse: coll=
apse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 100=
%;-webkit-text-size-adjust: 100%;">
    <tbody class=3D"mcnTextBlockOuter">
        <tr>
            <td valign=3D"top" class=3D"mcnTextBlockInner" style=3D"paddin=
g-top: 9px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webki=
t-text-size-adjust: 100%;">
              =09<!--[if mso]>
=09=09=09=09<table align=3D"left" border=3D"0" cellspacing=3D"0" cellpaddi=
ng=3D"0" width=3D"100%" style=3D"width:100%;">
=09=09=09=09<tr>
=09=09=09=09<![endif]-->
=09=09=09
=09=09=09=09<!--[if mso]>
=09=09=09=09<td valign=3D"top" width=3D"NaN" style=3D"width:NaNpx;">
=09=09=09=09<![endif]-->
                <table align=3D"left" border=3D"0" cellpadding=3D"0" cells=
pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
                    <tbody><tr>

                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding: 0px 18px 9px;color: #222222;font-family: Arial=2C &quot;Helve=
tica Neue&quot;=2C Helvetica=2C sans-serif;font-size: 16px;font-weight: no=
rmal;text-align: left;mso-line-height-rule: exactly;-ms-text-size-adjust:=
 100%;-webkit-text-size-adjust: 100%;word-break: break-word;line-height: 1=
50%;">

                            <!-- Section Label -->
<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
margin-bottom: 16px;border-collapse: collapse;mso-table-lspace: 0pt;mso-ta=
ble-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;=
" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"background-color: #1754ff;border-radius: 2px;mso-lin=
e-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust=
: 100%;" width=3D"4">&nbsp;</td>
=09=09=09<td style=3D"padding-left: 8px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<p style=3D"margin: 0px;font-family: &quot;Helvetica Neue&quot;=
=2C Helvetica=2C Arial=2C sans-serif;font-weight: 700;text-transform: uppe=
rcase;letter-spacing: 1px;padding: 0;mso-line-height-rule: exactly;-ms-tex=
t-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #222222;font-siz=
e: 18px;line-height: 150%;text-align: left;"><font color=3D"#000000"><span=
 style=3D"font-size:15px">FORUMs CONVERSATIONs</span></font></p>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>
<!-- Intro Text --><!-- Feed Block --><br>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://alsnewstoday.us5.list-manag=
e.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D99c24b4271&e=3D006462e992" style=3D"text-decoration: none;color: #000000;mso-line-height-rule:=
 exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-we=
ight: normal;" target=3D"_blank">SOD1 ALS &#8211; QALSody treatment</a></h=
3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://alsnewstoday.us5.list-manag=
e.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D1d84f22771&e=3D006462e992" style=3D"text-decoration: none;color: #000000;mso-line-height-rule:=
 exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-we=
ight: normal;" target=3D"_blank">SOD1 ALS &#8211; QALSody treatment</a></h=
3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://alsnewstoday.us5.list-manag=
e.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3Dfc44acf5e9&e=3D006462e992" style=3D"text-decoration: none;color: #000000;mso-line-height-rule:=
 exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-we=
ight: normal;" target=3D"_blank">What can you do to take care of your ment=
al health?</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

                        </td>
                    </tr>
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" style=3D"background: #ffffff none no-repeat center/cover;mso-line-height=
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ackground-color: #ffffff;background-image: none;background-repeat: no-repe=
at;background-position: center;background-size: cover;border-top: 0;border=
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                <table align=3D"left" border=3D"0" cellpadding=3D"0" cells=
pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
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                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding-top: 0;padding-right: 18px;padding-bottom: 9px;padding-left: 1=
8px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;word-break: break-word;color: #202020;font-family: Helve=
tica;font-size: 16px;line-height: 150%;text-align: left;">


<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #ffffff;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;"><!-- Article Title (Bo=
ld) -->
=09=09=09<h2 style=3D"margin: 0 0 12px 0;font-family: 'Helvetica Neue'=2C=
 Helvetica=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color:=
 #000000;line-height: 1.3;display: block;padding: 0;font-style: normal;let=
ter-spacing: normal;text-align: left;"><a href=3D"https://alsnewstoday.us5=
=2Elist-manage.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D7d13774a9a=
&e=3D006462e992" style=3D"text-decoration: none;color: #000000;mso-line-h=
eight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 1=
00%;font-weight: normal;"><strong>Accessible travel granted my late husban=
d normalcy=2C independence</strong> </a></h2>
=09=09=09<!-- Article Content Preview (Black=2C 16px) -->

=09=09=09<div style=3D"font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C sans-serif; font-size: 14px; color: #000000; line-height: 1.6; margin:=
0 0 16px 0;"><a href=3D"https://alsnewstoday.us5.list-manage.com/track/cli=
ck?u=3D52c64784d386bd00ea57ee792&id=3D3c3188036c&e=3D006462e992" title=3D=
"Accessible travel granted my late husband normalcy=2C independence" rel=
=3D"nofollow" style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust:=
 100%;-webkit-text-size-adjust: 100%;color: #1e2559;font-weight: normal;te=
xt-decoration: underline;"><img width=3D"800" src=3D"https://alsnewstoday.=
com/wp-content/uploads/2022/08/JulietTaylor_ThunderRoad-800x300.jpg" class=
=3D"webfeedsFeaturedVisual wp-post-image mcRssImage" alt=3D"Banner for Jul=
iet Taylor's column &quot;Thunder Road.&quot; The graphic depicts a couple=
 on a pier overlooking a lake=2C mountains=2C and forest." style=3D"max-wi=
dth: 100%;width: 100%;padding-bottom: 0;display: inline;vertical-align: bo=
ttom;border: 0;height: auto;outline: none;text-decoration: none;-ms-interp=
olation-mode: bicubic;" link_thumbnail=3D"1" decoding=3D"async" loading=3D=
"lazy" srcset=3D"https://alsnewstoday.com/wp-content/uploads/2022/08/Julie=
tTaylor_ThunderRoad-800x300.jpg 800w=2C https://alsnewstoday.com/wp-conten=
t/uploads/2022/08/JulietTaylor_ThunderRoad-380x143.jpg 380w=2C https://als=
newstoday.com/wp-content/uploads/2022/08/JulietTaylor_ThunderRoad-768x288.=
jpg 768w=2C https://alsnewstoday.com/wp-content/uploads/2022/08/JulietTayl=
or_ThunderRoad-1536x576.jpg 1536w=2C https://alsnewstoday.com/wp-content/u=
ploads/2022/08/JulietTaylor_ThunderRoad-1200x450.jpg 1200w=2C https://alsn=
ewstoday.com/wp-content/uploads/2022/08/JulietTaylor_ThunderRoad.jpg 1800w=
" sizes=3D"(max-width: 800px) 100vw=2C 800px" border=3D"0"></a><p style=3D=
"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-text-size-adj=
ust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-family: Helve=
tica;font-size: 16px;line-height: 150%;text-align: left;">I=E2=80=99m writ=
ing this column from vacation in a place I once traveled with my late husb=
and=2C Jeff=2C long before he was diagnosed with ALS in 2018. It was a dre=
am trip of his=2C and we went together for his birthday more than a decade=
 ago. On this trip=2C we traversed cobblestone streets=2C walked the beach=
=2C [&#8230;]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-fa=
mily: Helvetica;font-size: 16px;line-height: 150%;text-align: left;">The p=
ost <a href=3D"https://alsnewstoday.us5.list-manage.com/track/click?u=3D52=
c64784d386bd00ea57ee792&id=3D94c8b674db&e=3D006462e992" style=3D"mso-line=
-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust:=
 100%;color: #1e2559;font-weight: normal;text-decoration: underline;">Acce=
ssible travel granted my late husband normalcy=2C independence</a> appeare=
d first on <a href=3D"https://alsnewstoday.us5.list-manage.com/track/click=
?u=3D52c64784d386bd00ea57ee792&id=3D0dd55a1a1f&e=3D006462e992" style=3D"m=
so-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-=
adjust: 100%;color: #1e2559;font-weight: normal;text-decoration: underline=
;">ALS News Today</a>.</p></div>
=09=09=09<!-- Continue Reading Button (Filled Blue) --><a href=3D"https://=
alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee792=
&id=3D8a84d38651&e=3D006462e992" style=3D"display: inline-block;padding:=
 12px 24px;background-color: #1754FF;color: #ffffff;font-family: 'Helvetic=
a Neue'=2C Helvetica=2C Arial=2C sans-serif;font-size: 14px;font-weight: 6=
00;text-decoration: none;border-radius: 6px;mso-line-height-rule: exactly;=
-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">Continue Readi=
ng </a></td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #ffffff;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;"><!-- Article Title (Bo=
ld) -->
=09=09=09<h2 style=3D"margin: 0 0 12px 0;font-family: 'Helvetica Neue'=2C=
 Helvetica=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color:=
 #000000;line-height: 1.3;display: block;padding: 0;font-style: normal;let=
ter-spacing: normal;text-align: left;"><a href=3D"https://alsnewstoday.us5=
=2Elist-manage.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3De6e4523dbf=
&e=3D006462e992" style=3D"text-decoration: none;color: #000000;mso-line-h=
eight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 1=
00%;font-weight: normal;"><strong>Amylyx advancing ALS treatment in trial=
 after early safety data is positive</strong> </a></h2>
=09=09=09<!-- Article Content Preview (Black=2C 16px) -->

=09=09=09<div style=3D"font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C sans-serif; font-size: 14px; color: #000000; line-height: 1.6; margin:=
0 0 16px 0;"><a href=3D"https://alsnewstoday.us5.list-manage.com/track/cli=
ck?u=3D52c64784d386bd00ea57ee792&id=3D77d520a229&e=3D006462e992" title=3D=
"Amylyx advancing ALS treatment in trial after early safety data is positi=
ve" rel=3D"nofollow" style=3D"mso-line-height-rule: exactly;-ms-text-size-=
adjust: 100%;-webkit-text-size-adjust: 100%;color: #1e2559;font-weight: no=
rmal;text-decoration: underline;"><img width=3D"700" src=3D"https://alsnew=
stoday.com/wp-content/uploads/2023/05/Now-Recruiting-6.png" class=3D"webfe=
edsFeaturedVisual wp-post-image mcRssImage" alt=3D"A black curving line is=
 seen under the words &quot;Now Recruiting=2C&quot; written in red." style=
=3D"max-width: 100%;width: 100%;padding-bottom: 0;display: inline;vertical=
-align: bottom;border: 0;height: auto;outline: none;text-decoration: none;=
-ms-interpolation-mode: bicubic;" link_thumbnail=3D"1" decoding=3D"async"=
 loading=3D"lazy" srcset=3D"https://alsnewstoday.com/wp-content/uploads/20=
23/05/Now-Recruiting-6.png 700w=2C https://alsnewstoday.com/wp-content/upl=
oads/2023/05/Now-Recruiting-6-380x190.png 380w" sizes=3D"(max-width: 700px=
) 100vw=2C 700px" border=3D"0"></a><p style=3D"margin: 10px 0;padding: 0;m=
so-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-=
adjust: 100%;color: #202020;font-family: Helvetica;font-size: 16px;line-he=
ight: 150%;text-align: left;">The lowest tested dose of=C2=A0Amylyx Pharma=
ceuticals&#8216; treatment candidate AMX0114 was found to be safe and well=
 tolerated among people with amyotrophic lateral sclerosis (ALS) in an ong=
oing Phase 1 clinical trial. Biomarkers of nerve damage due to ALS remaine=
d relatively stable from the study&#8217;s start =E2=80=94 a result the tr=
ial investigators believe may change with [&#8230;]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-fa=
mily: Helvetica;font-size: 16px;line-height: 150%;text-align: left;">The p=
ost <a href=3D"https://alsnewstoday.us5.list-manage.com/track/click?u=3D52=
c64784d386bd00ea57ee792&id=3D8859fdeed8&e=3D006462e992" style=3D"mso-line=
-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust:=
 100%;color: #1e2559;font-weight: normal;text-decoration: underline;">Amyl=
yx advancing ALS treatment in trial after early safety data is positive</a=
> appeared first on <a href=3D"https://alsnewstoday.us5.list-manage.com/tr=
ack/click?u=3D52c64784d386bd00ea57ee792&id=3Dde908c8855&e=3D006462e992" s=
tyle=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-t=
ext-size-adjust: 100%;color: #1e2559;font-weight: normal;text-decoration:=
 underline;">ALS News Today</a>.</p></div>
=09=09=09<!-- Continue Reading Button (Filled Blue) --><a href=3D"https://=
alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee792=
&id=3D8eb59334c4&e=3D006462e992" style=3D"display: inline-block;padding:=
 12px 24px;background-color: #1754FF;color: #ffffff;font-family: 'Helvetic=
a Neue'=2C Helvetica=2C Arial=2C sans-serif;font-size: 14px;font-weight: 6=
00;text-decoration: none;border-radius: 6px;mso-line-height-rule: exactly;=
-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">Continue Readi=
ng </a></td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #ffffff;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;"><!-- Article Title (Bo=
ld) -->
=09=09=09<h2 style=3D"margin: 0 0 12px 0;font-family: 'Helvetica Neue'=2C=
 Helvetica=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color:=
 #000000;line-height: 1.3;display: block;padding: 0;font-style: normal;let=
ter-spacing: normal;text-align: left;"><a href=3D"https://alsnewstoday.us5=
=2Elist-manage.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3Dcaf6f772d8=
&e=3D006462e992" style=3D"text-decoration: none;color: #000000;mso-line-h=
eight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 1=
00%;font-weight: normal;"><strong>Planting seeds of hope in life with ALS<=
/strong> </a></h2>
=09=09=09<!-- Article Content Preview (Black=2C 16px) -->

=09=09=09<div style=3D"font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C sans-serif; font-size: 14px; color: #000000; line-height: 1.6; margin:=
0 0 16px 0;"><a href=3D"https://alsnewstoday.us5.list-manage.com/track/cli=
ck?u=3D52c64784d386bd00ea57ee792&id=3D9b50cc3929&e=3D006462e992" title=3D=
"Planting seeds of hope in life with ALS" rel=3D"nofollow" style=3D"mso-li=
ne-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjus=
t: 100%;color: #1e2559;font-weight: normal;text-decoration: underline;"><i=
mg width=3D"800" src=3D"https://alsnewstoday.com/wp-content/uploads/2020/0=
9/kristinneva_joyfulsorrow-1024x384.jpg" class=3D"webfeedsFeaturedVisual w=
p-post-image mcRssImage" alt=3D"Main graphic for &quot;Joyful Sorrow&quot;=
 column by Kristin Neva" style=3D"max-width: 100%;width: 100%;padding-bott=
om: 0;display: inline;vertical-align: bottom;border: 0;height: auto;outlin=
e: none;text-decoration: none;-ms-interpolation-mode: bicubic;" link_thumb=
nail=3D"1" decoding=3D"async" loading=3D"lazy" srcset=3D"https://alsnewsto=
day.com/wp-content/uploads/2020/09/kristinneva_joyfulsorrow-1024x384.jpg 1=
024w=2C https://alsnewstoday.com/wp-content/uploads/2020/09/kristinneva_jo=
yfulsorrow-300x113.jpg 300w=2C https://alsnewstoday.com/wp-content/uploads=
/2020/09/kristinneva_joyfulsorrow-768x288.jpg 768w=2C https://alsnewstoday=
=2Ecom/wp-content/uploads/2020/09/kristinneva_joyfulsorrow-1200x450.jpg 1200=
w=2C https://alsnewstoday.com/wp-content/uploads/2020/09/kristinneva_joyfu=
lsorrow.jpg 1400w" sizes=3D"(max-width: 800px) 100vw=2C 800px" border=3D"0=
"></a><p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;=
-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;f=
ont-family: Helvetica;font-size: 16px;line-height: 150%;text-align: left;"=
>A couple months ago=2C I planted zinnia and strawflower seeds in two plas=
tic bins and set them in the sunlight under our patio window in my dining=
 room. I=E2=80=99ve grown vegetables from seeds in the past=2C but never f=
lowers. Vegetables feel practical because food is necessary to sustain lif=
e=2C while growing flowers feels like a [&#8230;]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-fa=
mily: Helvetica;font-size: 16px;line-height: 150%;text-align: left;">The p=
ost <a href=3D"https://alsnewstoday.us5.list-manage.com/track/click?u=3D52=
c64784d386bd00ea57ee792&id=3D4863ee5739&e=3D006462e992" style=3D"mso-line=
-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust:=
 100%;color: #1e2559;font-weight: normal;text-decoration: underline;">Plan=
ting seeds of hope in life with ALS</a> appeared first on <a href=3D"https=
://alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee=
792&id=3D35803499f4&e=3D006462e992" style=3D"mso-line-height-rule: exactl=
y;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #1e2559=
;font-weight: normal;text-decoration: underline;">ALS News Today</a>.</p><=
/div>
=09=09=09<!-- Continue Reading Button (Filled Blue) --><a href=3D"https://=
alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee792=
&id=3Dd57e5eb8f9&e=3D006462e992" style=3D"display: inline-block;padding:=
 12px 24px;background-color: #1754FF;color: #ffffff;font-family: 'Helvetic=
a Neue'=2C Helvetica=2C Arial=2C sans-serif;font-size: 14px;font-weight: 6=
00;text-decoration: none;border-radius: 6px;mso-line-height-rule: exactly;=
-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">Continue Readi=
ng </a></td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #ffffff;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;"><!-- Article Title (Bo=
ld) -->
=09=09=09<h2 style=3D"margin: 0 0 12px 0;font-family: 'Helvetica Neue'=2C=
 Helvetica=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color:=
 #000000;line-height: 1.3;display: block;padding: 0;font-style: normal;let=
ter-spacing: normal;text-align: left;"><a href=3D"https://alsnewstoday.us5=
=2Elist-manage.com/track/click?u=3D52c64784d386bd00ea57ee792&id=3D25fd6a93a9=
&e=3D006462e992" style=3D"text-decoration: none;color: #000000;mso-line-h=
eight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 1=
00%;font-weight: normal;"><strong>New European trial testing safety of ALS=
 therapy targeting fat metabolism</strong> </a></h2>
=09=09=09<!-- Article Content Preview (Black=2C 16px) -->

=09=09=09<div style=3D"font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C sans-serif; font-size: 14px; color: #000000; line-height: 1.6; margin:=
0 0 16px 0;"><a href=3D"https://alsnewstoday.us5.list-manage.com/track/cli=
ck?u=3D52c64784d386bd00ea57ee792&id=3Db37906a226&e=3D006462e992" title=3D=
"New European trial testing safety of ALS therapy targeting fat metabolism=
" rel=3D"nofollow" style=3D"mso-line-height-rule: exactly;-ms-text-size-ad=
just: 100%;-webkit-text-size-adjust: 100%;color: #1e2559;font-weight: norm=
al;text-decoration: underline;"><img width=3D"700" src=3D"https://alsnewst=
oday.com/wp-content/uploads/2026/02/EnrollNow.png" class=3D"webfeedsFeatur=
edVisual wp-post-image mcRssImage" alt=3D"A person sits at a computer with=
 &quot;ENROLL NOW&quot; displayed on the monitor." style=3D"max-width: 100=
%;width: 100%;padding-bottom: 0;display: inline;vertical-align: bottom;bor=
der: 0;height: auto;outline: none;text-decoration: none;-ms-interpolation-=
mode: bicubic;" link_thumbnail=3D"1" decoding=3D"async" loading=3D"lazy" s=
rcset=3D"https://alsnewstoday.com/wp-content/uploads/2026/02/EnrollNow.png=
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x190.png 380w" sizes=3D"(max-width: 700px) 100vw=2C 700px" border=3D"0"></=
a><p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-=
family: Helvetica;font-size: 16px;line-height: 150%;text-align: left;">The=
 first patient has been dosed in a Phase 1/2 clinical trial evaluating Lea=
l Therapeutics&#8216; LTX-002=2C an antisense oligonucleotide designed to=
 target abnormalities in fat metabolism that may contribute to amyotrophic=
 lateral sclerosis=C2=A0(ALS). The NeurALS trial (NCT07660614) is now recr=
uiting an estimated 56 adults with ALS at two sites in Europe=2C with plan=
s to add [&#8230;]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-fa=
mily: Helvetica;font-size: 16px;line-height: 150%;text-align: left;">The p=
ost <a href=3D"https://alsnewstoday.us5.list-manage.com/track/click?u=3D52=
c64784d386bd00ea57ee792&id=3Db40fa599ab&e=3D006462e992" style=3D"mso-line=
-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust:=
 100%;color: #1e2559;font-weight: normal;text-decoration: underline;">New=
 European trial testing safety of ALS therapy targeting fat metabolism</a>=
 appeared first on <a href=3D"https://alsnewstoday.us5.list-manage.com/tra=
ck/click?u=3D52c64784d386bd00ea57ee792&id=3De00b939333&e=3D006462e992" st=
yle=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-te=
xt-size-adjust: 100%;color: #1e2559;font-weight: normal;text-decoration: u=
nderline;">ALS News Today</a>.</p></div>
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alsnewstoday.us5.list-manage.com/track/click?u=3D52c64784d386bd00ea57ee792=
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a Neue'=2C Helvetica=2C Arial=2C sans-serif;font-size: 14px;font-weight: 6=
00;text-decoration: none;border-radius: 6px;mso-line-height-rule: exactly;=
-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">Continue Readi=
ng </a></td>
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=3D"padding-top: 0;padding-right: 18px;padding-bottom: 9px;padding-left: 1=
8px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
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tica;font-size: 16px;line-height: 200%;text-align: left;">

                            <div style=3D"text-align: center;"><span style=
=3D"font-size:14px"><em><strong>Follow us on social media for exclusive co=
ntent=2C and visit our website to learn about our Advocacy Partners: The A=
LS Association=2C Muscular Dystrophy Association=2C and The ALS Network</s=
trong></em></span></div>

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