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** Higher microplastic levels seen in people with newly diagnosed ALS (htt=
ps://us.list-manage.com/1AHefwMI4H4?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DFyHuLzTvgB10Ji_QTGrRxmn3WuqMQFA0W_-mMlBvWsGOGOb68fz1xygS9k8bZncjlVoLmTNV4uanCShVh1AOJqbdNw=3D=3D)
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A buildup of microplastics in the nervous system may be linked to a higher=
 risk of developing amyotrophic lateral sclerosis (ALS)=2C according to a=
 new study. People newly diagnosed with the neurodegenerative disease were=
 found to have higher concentrations of tiny plastic particles in both the=
ir blood and the fluid surrounding their brain and spinal [=E2=80=A6]

The post Higher microplastic levels seen in people with newly diagnosed AL=
S (https://us.list-manage.com/LSvpZjsS2HA?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DozbiRLa5hLnYGXKRoWU0kHtKuHgoAyWf5Wj_0FRBYaOYmT7HoLWf_G2Dhy9x) appeared first on=
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** Newer ALS diagnostic criteria more sensitive than older approaches (htt=
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A newer set of diagnostic criteria for amyotrophic lateral sclerosis (ALS)=
 was significantly more sensitive at identifying people with the disease t=
han two older diagnostic approaches=2C a real-world study in Germany found=
=2E Among more than 400 people ultimately diagnosed with ALS=2C these Gold C=
oast criteria correctly identified 92.5% of ALS cases=2C compared with les=
s than [=E2=80=A6]

The post Newer ALS diagnostic criteria more sensitive than older approache=
s (https://us.list-manage.com/Crs14u65jpj?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3Do5hWnE3qICKZTJBVGh2_VE9JMGamShVZ2Al2YW2TXwhXx8jRMq8ooqAtY9kf) appeared first on=
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** Putting a spotlight on the challenges of being a caregiver (https://us.=
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The challenges of caregiving have been in the news lately. Last year=2C Do=
lly Parton appeared in a video following the death of her husband=2C Carl=
 Dean=2C to quell rumors about her own poor health after the cancellation=
 of some shows. She said=2C =E2=80=9CBack when my husband=2C Carl=2C was v=
ery sick=2C that was for a long time=2C [=E2=80=A6]

The post Putting a spotlight on the challenges of being a caregiver (https=
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=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DpdhnRSY0J5Hwodi7kIiuNtpy6wfrBzbfJM4Ma3xnJj6VfwAFrjUt5sDvaaLk) .
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** Revamped plan aims to hasten US approval of treatment for ALS (https://=
us.list-manage.com/kVgaEYXRr7S?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D3DhmQRgHbYCBvpdmh3jXwSFleJR-rSm2-klAdS_YgIwhGYqsLQJHk-eRdOBW4hn9AcJgW7nLcw18cqErEsFLMjkg9g=3D=3D)
------------------------------------------------------------
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Neurosense Therapeutics is revamping its development plan for PrimeC=2C th=
e company=E2=80=99s experimental oral therapy for amyotrophic lateral scle=
rosis (ALS). The updated plan includes a new study that will directly comp=
are PrimeC against an approved ALS treatment=2C as well as a restructured=
 Phase 3 trial and analyses of existing data using artificial intelligence=
 (AI). With these [=E2=80=A6]

The post Revamped plan aims to hasten US approval of treatment for ALS (ht=
tps://us.list-manage.com/d6Wpj9w7Sa5?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DbyKpHdX362GPz4KsSQeHQ6efklX2cE-jdecOQIhuneZ_qVASzZcrRRw_GOf3) appeared first on ALS=
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=09=09=09<td style=3D"background-color: #1754ff;border-radius: 2px;mso-lin=
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=09=09=09<td style=3D"padding-left: 8px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
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=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
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LkE?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D_mCk41zlLrEQZJQgZI4A3tkB5zviNA5V140nfz-fkoFeJX3SduHL1qW7ePWgjG8YPid8gayVy830aC_JF2VZzZ5cpw=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
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t: normal;" target=3D"_blank">Higher microplastic levels seen in people wi=
th newly diagnosed ALS</a></h3>
=09=09=09</td>
=09=09</tr>
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<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
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=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
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Xxo?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D-69X3QnoiNHd8nCfYhTE-yYe_iHm7sMzNDDPdxAyaCWgHcOVMo7nq7IvB4W6zGgjrmZe8khxG1QHE5Mtgu2bs9-DPA=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">Newer ALS diagnostic criteria more sensitive=
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=09=09=09</td>
=09=09</tr>
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background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
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=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
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Jey?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DCjJH7nzmr-RT9t4lNqUEAe8hj2c9YFkpnjUxnTG5sBbSu3oAjWQpNd4CJi8HWhhX4yksEbN6ixe68cZokix9UO7_kw=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
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t: normal;" target=3D"_blank">Revamped plan aims to hasten US approval of=
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=09=09=09</td>
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=09=09=09<td style=3D"background-color: #05D3AB;border-radius: 2px;mso-lin=
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text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
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e: 18px;line-height: 150%;text-align: left;"><font color=3D"#000000"><span=
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=09=09</tr>
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<!-- Intro Text --><!-- Feed Block --><br>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
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=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
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=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
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ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
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yQg?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DP3loSPtBML0XSGmIn2-pztofBbob9BLZGqBFdvBI49nsnrRnXEWZ8DzBi5PcAwF5UpQ4zP04lFxFq584Ckiujw_TXw=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
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t: normal;" target=3D"_blank">Putting a spotlight on the challenges of bei=
ng a caregiver</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
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=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
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uYW?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DK6kgY5ozXfb4V-xwObM_B_eO9BKaZGKIQ0pPuEEj3IFU4nOVoEAzK4CzOYNSST3mBmQd7WGN44noiyYYvK2xqAqMmw=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
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=09=09=09</td>
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<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
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=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
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t: normal;" target=3D"_blank">Guest Voice: What it means to be an ALS care=
giver</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

                        </td>
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pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
                    <tbody><tr>

                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding: 0px 18px 9px;color: #222222;font-family: Arial=2C &quot;Helve=
tica Neue&quot;=2C Helvetica=2C sans-serif;font-size: 16px;font-weight: no=
rmal;text-align: left;mso-line-height-rule: exactly;-ms-text-size-adjust:=
 100%;-webkit-text-size-adjust: 100%;word-break: break-word;line-height: 1=
50%;">

                            <!-- Section Label -->
<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
margin-bottom: 16px;border-collapse: collapse;mso-table-lspace: 0pt;mso-ta=
ble-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;=
" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"background-color: #1754ff;border-radius: 2px;mso-lin=
e-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust=
: 100%;" width=3D"4">&nbsp;</td>
=09=09=09<td style=3D"padding-left: 8px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<p style=3D"margin: 0px;font-family: &quot;Helvetica Neue&quot;=
=2C Helvetica=2C Arial=2C sans-serif;font-weight: 700;text-transform: uppe=
rcase;letter-spacing: 1px;padding: 0;mso-line-height-rule: exactly;-ms-tex=
t-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #222222;font-siz=
e: 18px;line-height: 150%;text-align: left;"><font color=3D"#000000"><span=
 style=3D"font-size:15px">FORUMs CONVERSATIONs</span></font></p>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>
<!-- Intro Text --><!-- Feed Block --><br>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/13Y0N3RQ=
jPp?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DbR2CkSlnC4aMTK8DDaM-sTIXYJw04sE4zUZPfOwxo0uZUf794c51TmR3aXEKsdySBc_EkLFf_iJHmPkbvcyQoQ1jKA=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">What=E2=80=99s one thing that ALS has made y=
ou rethink?</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/k9Nrg2PR=
hjo?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DvAmex2t1xHzhymtAJqLLOLQYpCnj7JNXSwZpcdwotGE-XGE609lvZIGgGVe63MUDtq_92l2jxTfAWY7RJQTIqq2eaA=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">How has ALS positively affected your life?</=
a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

                        </td>
                    </tr>
                </tbody></table>
=09=09=09=09<!--[if mso]>
=09=09=09=09</td>
=09=09=09=09<![endif]-->

=09=09=09=09<!--[if mso]>
=09=09=09=09</tr>
=09=09=09=09</table>
=09=09=09=09<![endif]-->
            </td>
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</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnDividerBlock" style=3D"min-width: 100%;border-collapse: c=
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            <td class=3D"mcnDividerBlockInner" style=3D"min-width: 100%;pa=
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table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100=
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</table></td>
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                                <td valign=3D"top" id=3D"templateUpperBody=
" style=3D"background: #ffffff none no-repeat center/cover;mso-line-height=
-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;b=
ackground-color: #ffffff;background-image: none;background-repeat: no-repe=
at;background-position: center;background-size: cover;border-top: 0;border=
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g-top: 9px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webki=
t-text-size-adjust: 100%;">
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=09=09=09=09<td valign=3D"top" width=3D"NaN" style=3D"width:NaNpx;">
=09=09=09=09<![endif]-->
                <table align=3D"left" border=3D"0" cellpadding=3D"0" cells=
pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
                    <tbody><tr>

                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding: 0px 18px 9px;color: #222222;font-family: Arial=2C &quot;Helve=
tica Neue&quot;=2C Helvetica=2C sans-serif;font-size: 16px;font-weight: no=
rmal;text-align: left;mso-line-height-rule: exactly;-ms-text-size-adjust:=
 100%;-webkit-text-size-adjust: 100%;word-break: break-word;line-height: 1=
50%;">

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<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
margin-bottom: 16px;border-collapse: collapse;mso-table-lspace: 0pt;mso-ta=
ble-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;=
" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"background-color: #05D3AB;border-radius: 2px;mso-lin=
e-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust=
: 100%;" width=3D"4">&nbsp;</td>
=09=09=09<td style=3D"padding-left: 8px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<p style=3D"margin: 0px;font-family: &quot;Helvetica Neue&quot;=
=2C Helvetica=2C Arial=2C sans-serif;font-weight: 700;text-transform: uppe=
rcase;letter-spacing: 1px;padding: 0;mso-line-height-rule: exactly;-ms-tex=
t-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-siz=
e: 16px;line-height: 150%;text-align: left;"><font color=3D"#000000"><span=
 style=3D"font-size:15px">Featured Content&nbsp;</span></font></p>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>
<!-- Intro Text --><!-- Feed Block --><br>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/zW73nW4K=
VXI?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3Dxgpm5ficxPXa-L2omlGEyGeDixTTe34nOuJRcuca76ePFNuFnGS9emQoDbKdII69poIOmCJnBvT215IH_ADInEz07w=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">Therapeutic synergy: Benefits of a multiface=
ted ALS treatment strategy</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/uyboX6MH=
rc4?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DNQa2KbDz1R2LFxVCkxJzsJ4orGWbKZ6PfseJy-XorhBINtQk9n1rsZWYl58iDMIqwxHF0RDVWXFX0H_rwFu1m6oo6Q=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">Next steps after an ALS diagnosis</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

                        </td>
                    </tr>
                </tbody></table>
=09=09=09=09<!--[if mso]>
=09=09=09=09</td>
=09=09=09=09<![endif]-->

=09=09=09=09<!--[if mso]>
=09=09=09=09</tr>
=09=09=09=09</table>
=09=09=09=09<![endif]-->
            </td>
        </tr>
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</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnDividerBlock" style=3D"min-width: 100%;border-collapse: c=
ollapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust:=
 100%;-webkit-text-size-adjust: 100%;table-layout: fixed !important;">
    <tbody class=3D"mcnDividerBlockOuter">
        <tr>
            <td class=3D"mcnDividerBlockInner" style=3D"min-width: 100%;pa=
dding: 5px 18px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-=
webkit-text-size-adjust: 100%;">
                <table class=3D"mcnDividerContent" border=3D"0" cellpaddin=
g=3D"0" cellspacing=3D"0" width=3D"100%" style=3D"min-width: 100%;border-t=
op: 2px solid #EAEAEA;border-collapse: collapse;mso-table-lspace: 0pt;mso-=
table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100=
%;">
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t-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
                            <span></span>
                        </td>
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</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnTextBlock" style=3D"min-width: 100%;border-collapse: coll=
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g-top: 9px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webki=
t-text-size-adjust: 100%;">
              =09<!--[if mso]>
=09=09=09=09<table align=3D"left" border=3D"0" cellspacing=3D"0" cellpaddi=
ng=3D"0" width=3D"100%" style=3D"width:100%;">
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=09=09=09=09<![endif]-->
                <table align=3D"left" border=3D"0" cellpadding=3D"0" cells=
pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
                    <tbody><tr>

                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding-top: 0;padding-right: 18px;padding-bottom: 9px;padding-left: 1=
8px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;word-break: break-word;color: #202020;font-family: Helve=
tica;font-size: 16px;line-height: 150%;text-align: left;">


<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #ffffff;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;"><!-- Article Title (Bo=
ld) -->
=09=09=09<h2 style=3D"margin: 0 0 12px 0;font-family: 'Helvetica Neue'=2C=
 Helvetica=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color:=
 #000000;line-height: 1.3;display: block;padding: 0;font-style: normal;let=
ter-spacing: normal;text-align: left;"><a href=3D"https://us.list-manage.c=
om/12uM_brFOb5?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DNvyyisuM564oSDbw3hUiXZWs5vxgNcw8iy9LAJGLctAGZqowzgHiEkzVSa4dyFnQUSR6YQ8DB27dYfm0ljgtzSaK4g=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-heig=
ht-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%=
;font-weight: normal;"><strong>Higher microplastic levels seen in people w=
ith newly diagnosed ALS</strong> </a></h2>
=09=09=09<!-- Article Content Preview (Black=2C 16px) -->

=09=09=09<div style=3D"font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C sans-serif; font-size: 14px; color: #000000; line-height: 1.6; margin:=
0 0 16px 0;"><a href=3D"https://us.list-manage.com/cru36J5peD7?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DZXh32yTzXe4eGvzn3m28A_Yrnki11oRffAXuWlzm-IXva-9MRS0ODt6itiz4" title=3D"Hi=
gher microplastic levels seen in people with newly diagnosed ALS" rel=3D"n=
ofollow" style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%=
;-webkit-text-size-adjust: 100%;color: #1e2559;font-weight: normal;text-de=
coration: underline;"><img width=3D"700" src=3D"https://alsnewstoday.com/w=
p-content/uploads/2025/05/BrainProfile.png" class=3D"webfeedsFeaturedVisua=
l wp-post-image mcRssImage" alt=3D"A person's brain is seen in profile." s=
tyle=3D"max-width: 100%;width: 100%;padding-bottom: 0;display: inline;vert=
ical-align: bottom;border: 0;height: auto;outline: none;text-decoration: n=
one;-ms-interpolation-mode: bicubic;" link_thumbnail=3D"1" decoding=3D"asy=
nc" loading=3D"lazy" srcset=3D"https://alsnewstoday.com/wp-content/uploads=
/2025/05/BrainProfile.png 700w=2C https://alsnewstoday.com/wp-content/uplo=
ads/2025/05/BrainProfile-380x190.png 380w" sizes=3D"(max-width: 700px) 100=
vw=2C 700px" border=3D"0"></a><p style=3D"margin: 10px 0;padding: 0;mso-li=
ne-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjus=
t: 100%;color: #202020;font-family: Helvetica;font-size: 16px;line-height:=
 150%;text-align: left;">A buildup of microplastics in the nervous system=
 may be linked to a higher risk of developing amyotrophic lateral sclerosi=
s (ALS)=2C according to a new study. People newly diagnosed with the neuro=
degenerative disease were found to have higher concentrations of tiny plas=
tic particles in both their blood and the fluid surrounding their brain an=
d spinal [&#8230;]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-fa=
mily: Helvetica;font-size: 16px;line-height: 150%;text-align: left;">The p=
ost <a href=3D"https://us.list-manage.com/O2vpMqEqQdj?e=3D006462e992&c2id=
=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DcqaVCo9cYPA0AbwuDaN6hcQUyFQNQFeN25st3zpO4l1yHC1KzczwLuczIkfO" style=3D"mso-line-he=
ight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 10=
0%;color: #1e2559;font-weight: normal;text-decoration: underline;">Higher=
 microplastic levels seen in people with newly diagnosed ALS</a> appeared=
 first on <a href=3D"https://us.list-manage.com/I3BDzEUHC4I?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D8dXrGv9out-4LIm62UXWw6Gs1k5oGyUL-HAlEdCcCCm5q-_S_kNrOk04w-qQ" style=3D"mso-l=
ine-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adju=
st: 100%;color: #1e2559;font-weight: normal;text-decoration: underline;">A=
LS News Today</a>.</p></div>
=09=09=09<!-- Continue Reading Button (Filled Blue) --><a href=3D"https://=
us.list-manage.com/NkpHtujTikT?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D4AdrsjuJ0mBhI1_4NSWuGaWnorpaVCXdBnZpYHdQxQ8iRB5e8kqKfWOv0X_JQbdcBn6oPQBmTW5hL6F7OIJi9tDLYQ=3D=3D" style=3D"display: inline-block;padding: 12p=
x 24px;background-color: #1754FF;color: #ffffff;font-family: 'Helvetica Ne=
ue'=2C Helvetica=2C Arial=2C sans-serif;font-size: 14px;font-weight: 600;t=
ext-decoration: none;border-radius: 6px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">Continue Reading <=
/a></td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #ffffff;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;"><!-- Article Title (Bo=
ld) -->
=09=09=09<h2 style=3D"margin: 0 0 12px 0;font-family: 'Helvetica Neue'=2C=
 Helvetica=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color:=
 #000000;line-height: 1.3;display: block;padding: 0;font-style: normal;let=
ter-spacing: normal;text-align: left;"><a href=3D"https://us.list-manage.c=
om/7fhtHeU_U8D?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D0vZbvIbmKsfhEdfMpc-sZIc6-luERzpN5flJabmaQl-q3ceWBPVB32fCJWbwwXSk7MoR-LT7OJj7kbCBYotzsvFyuA=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-heig=
ht-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%=
;font-weight: normal;"><strong>Newer ALS diagnostic criteria more sensitiv=
e than older approaches</strong> </a></h2>
=09=09=09<!-- Article Content Preview (Black=2C 16px) -->

=09=09=09<div style=3D"font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C sans-serif; font-size: 14px; color: #000000; line-height: 1.6; margin:=
0 0 16px 0;"><a href=3D"https://us.list-manage.com/tonw06wKNzK?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DMcGArb1ThadWpwQfUzop8mUxItMv_gZy9I3pkqC6mN41In-0HBxDHSsKs4LP" title=3D"Ne=
wer ALS diagnostic criteria more sensitive than older approaches" rel=3D"n=
ofollow" style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%=
;-webkit-text-size-adjust: 100%;color: #1e2559;font-weight: normal;text-de=
coration: underline;"><img width=3D"700" src=3D"https://alsnewstoday.com/w=
p-content/uploads/2024/02/InTheNews.png" class=3D"webfeedsFeaturedVisual w=
p-post-image mcRssImage" alt=3D"A person in a lab coat uses a laser pointe=
r to point at the words &quot;in the news.&quot;" style=3D"max-width: 100%=
;width: 100%;padding-bottom: 0;display: inline;vertical-align: bottom;bord=
er: 0;height: auto;outline: none;text-decoration: none;-ms-interpolation-m=
ode: bicubic;" link_thumbnail=3D"1" decoding=3D"async" loading=3D"lazy" sr=
cset=3D"https://alsnewstoday.com/wp-content/uploads/2024/02/InTheNews.png=
 700w=2C https://alsnewstoday.com/wp-content/uploads/2024/02/InTheNews-380=
x190.png 380w" sizes=3D"(max-width: 700px) 100vw=2C 700px" border=3D"0"></=
a><p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-=
family: Helvetica;font-size: 16px;line-height: 150%;text-align: left;">A n=
ewer set of diagnostic criteria for amyotrophic lateral sclerosis (ALS) wa=
s significantly more sensitive at identifying people with the disease than=
 two older diagnostic approaches=2C a real-world study in Germany found. A=
mong more than 400 people ultimately diagnosed with ALS=2C these Gold Coas=
t criteria correctly identified 92.5% of ALS cases=2C compared with less t=
han [&#8230;]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-fa=
mily: Helvetica;font-size: 16px;line-height: 150%;text-align: left;">The p=
ost <a href=3D"https://us.list-manage.com/_O3QdZBalLw?e=3D006462e992&c2id=
=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DeIkWEb28g3uUxeCkNuKDi8VB1HGRoACWsu1gsHyNsUt04CNFT2cgyKFcan4C" style=3D"mso-line-he=
ight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 10=
0%;color: #1e2559;font-weight: normal;text-decoration: underline;">Newer A=
LS diagnostic criteria more sensitive than older approaches</a> appeared f=
irst on <a href=3D"https://us.list-manage.com/xLQR9mRAmGF?e=3D006462e992&=
c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DGTFw8rcKHkWEMC7K4LBnzfYEq--t7_Q0BJsI6UyZwsP_GT3xYaEz-fEfGO9W" style=3D"mso-lin=
e-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust=
: 100%;color: #1e2559;font-weight: normal;text-decoration: underline;">ALS=
 News Today</a>.</p></div>
=09=09=09<!-- Continue Reading Button (Filled Blue) --><a href=3D"https://=
us.list-manage.com/qLna2fCu78W?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DWOt70fTUesMN2Qs344Wm8gqfvyuV_7QifstdGRXad6b0hwR8C63OT2S0seqMpIDW4l-YXrsXWBWWe07rHM7U1tmeeA=3D=3D" style=3D"display: inline-block;padding: 12p=
x 24px;background-color: #1754FF;color: #ffffff;font-family: 'Helvetica Ne=
ue'=2C Helvetica=2C Arial=2C sans-serif;font-size: 14px;font-weight: 600;t=
ext-decoration: none;border-radius: 6px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">Continue Reading <=
/a></td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #ffffff;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;"><!-- Article Title (Bo=
ld) -->
=09=09=09<h2 style=3D"margin: 0 0 12px 0;font-family: 'Helvetica Neue'=2C=
 Helvetica=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color:=
 #000000;line-height: 1.3;display: block;padding: 0;font-style: normal;let=
ter-spacing: normal;text-align: left;"><a href=3D"https://us.list-manage.c=
om/wdpj8Sodv1I?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DXYC2GHRph81gNM72J8-aPJw0OT6y6V7sf0-PejzE_zTx1Ekfq30WRKeF628KY0snm0ESLJR-l6IvXeAlTQ6i1km-PQ=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-heig=
ht-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%=
;font-weight: normal;"><strong>Putting a spotlight on the challenges of be=
ing a caregiver</strong> </a></h2>
=09=09=09<!-- Article Content Preview (Black=2C 16px) -->

=09=09=09<div style=3D"font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C sans-serif; font-size: 14px; color: #000000; line-height: 1.6; margin:=
0 0 16px 0;"><a href=3D"https://us.list-manage.com/nahVNplS43v?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DBxhTdMn625Lzw9ITJUZH2UmaGiHu8_LAJamPkWGFG9ajNWQaIr8iRcLVyINn" title=3D"Pu=
tting a spotlight on the challenges of being a caregiver" rel=3D"nofollow"=
 style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit=
-text-size-adjust: 100%;color: #1e2559;font-weight: normal;text-decoration=
: underline;"><img width=3D"800" src=3D"https://alsnewstoday.com/wp-conten=
t/uploads/2020/09/kristinneva_joyfulsorrow-1024x384.jpg" class=3D"webfeeds=
FeaturedVisual wp-post-image mcRssImage" alt=3D"Main graphic for &quot;Joy=
ful Sorrow&quot; column by Kristin Neva." style=3D"max-width: 100%;width:=
 100%;padding-bottom: 0;display: inline;vertical-align: bottom;border: 0;h=
eight: auto;outline: none;text-decoration: none;-ms-interpolation-mode: bi=
cubic;" link_thumbnail=3D"1" decoding=3D"async" loading=3D"lazy" srcset=3D=
"https://alsnewstoday.com/wp-content/uploads/2020/09/kristinneva_joyfulsor=
row-1024x384.jpg 1024w=2C https://alsnewstoday.com/wp-content/uploads/2020=
/09/kristinneva_joyfulsorrow-300x113.jpg 300w=2C https://alsnewstoday.com/=
wp-content/uploads/2020/09/kristinneva_joyfulsorrow-768x288.jpg 768w=2C ht=
tps://alsnewstoday.com/wp-content/uploads/2020/09/kristinneva_joyfulsorrow=
-1200x450.jpg 1200w=2C https://alsnewstoday.com/wp-content/uploads/2020/09=
/kristinneva_joyfulsorrow.jpg 1400w" sizes=3D"(max-width: 800px) 100vw=2C=
 800px" border=3D"0"></a><p style=3D"margin: 10px 0;padding: 0;mso-line-he=
ight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 10=
0%;color: #202020;font-family: Helvetica;font-size: 16px;line-height: 150%=
;text-align: left;">The challenges of caregiving have been in the news lat=
ely. Last year=2C Dolly Parton appeared in a video following the death of=
 her husband=2C Carl Dean=2C to quell rumors about her own poor health aft=
er the cancellation of some shows.=C2=A0She said=2C =E2=80=9CBack when my=
 husband=2C Carl=2C was very sick=2C that was for a long time=2C [&#8230;=
]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-fa=
mily: Helvetica;font-size: 16px;line-height: 150%;text-align: left;">The p=
ost <a href=3D"https://us.list-manage.com/XjVGPtFMIFs?e=3D006462e992&c2id=
=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DsKql6RKRaTSwE3Rj7ZhnpX4AnVZA8np5jY7j_2tZ0LELufOSFtg2OIVqXz4A" style=3D"mso-line-he=
ight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 10=
0%;color: #1e2559;font-weight: normal;text-decoration: underline;">Putting=
 a spotlight on the challenges of being a caregiver</a> appeared first on=
 <a href=3D"https://us.list-manage.com/8ZbWa6XmNzi?e=3D006462e992&c2id=3D=
6d8df1454ee901f23d2c8d3973c45e87&m=3DVZVSydLRTspP_PclIjxJiAIWpDjFO2GTOjf2ykaNAh6_kSKJ3KCtk_GiH6NC" style=3D"mso-line-heigh=
t-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;=
color: #1e2559;font-weight: normal;text-decoration: underline;">ALS News T=
oday</a>.</p></div>
=09=09=09<!-- Continue Reading Button (Filled Blue) --><a href=3D"https://=
us.list-manage.com/ErcoxskVHeV?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3Dam7FEeL4g_KhkdcBSt-nqcSVTnIFG_pMuLXMHLCZbhJktzxy3zTnuDhIjqE7TNbYnnZzRiiPaAqwD4OYX1raiWqsLg=3D=3D" style=3D"display: inline-block;padding: 12p=
x 24px;background-color: #1754FF;color: #ffffff;font-family: 'Helvetica Ne=
ue'=2C Helvetica=2C Arial=2C sans-serif;font-size: 14px;font-weight: 600;t=
ext-decoration: none;border-radius: 6px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">Continue Reading <=
/a></td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #ffffff;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;"><!-- Article Title (Bo=
ld) -->
=09=09=09<h2 style=3D"margin: 0 0 12px 0;font-family: 'Helvetica Neue'=2C=
 Helvetica=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color:=
 #000000;line-height: 1.3;display: block;padding: 0;font-style: normal;let=
ter-spacing: normal;text-align: left;"><a href=3D"https://us.list-manage.c=
om/6nmvbUc22Fm?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DMFhaY5RSHvw0qo9NQ103ccJMLo8g9KocggeqT664wsP_ImRTx06EeZpxBK6_mTUCgjzgHCuwiR1iPdZPDoGWGf-yRw=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-heig=
ht-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%=
;font-weight: normal;"><strong>Revamped plan aims to hasten US approval of=
 treatment for ALS</strong> </a></h2>
=09=09=09<!-- Article Content Preview (Black=2C 16px) -->

=09=09=09<div style=3D"font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C sans-serif; font-size: 14px; color: #000000; line-height: 1.6; margin:=
0 0 16px 0;"><a href=3D"https://us.list-manage.com/130jUMjzWay?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3Db3r6zLwYiAcCwwB_F6Vhf6Caq4cG_xkHAMyOWY_Ekyrc6qetLTU4VDyprk1e" title=3D"Re=
vamped plan aims to hasten US approval of treatment for ALS" rel=3D"nofoll=
ow" style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-web=
kit-text-size-adjust: 100%;color: #1e2559;font-weight: normal;text-decorat=
ion: underline;"><img width=3D"700" src=3D"https://alsnewstoday.com/wp-con=
tent/uploads/2022/09/ClinicalTrialsClipboard.png" class=3D"webfeedsFeature=
dVisual wp-post-image mcRssImage" alt=3D"An oversized red pen ticks boxes=
 labeled Clinical and Trials on a clipboard checklist." style=3D"max-width=
: 100%;width: 100%;padding-bottom: 0;display: inline;vertical-align: botto=
m;border: 0;height: auto;outline: none;text-decoration: none;-ms-interpola=
tion-mode: bicubic;" link_thumbnail=3D"1" decoding=3D"async" loading=3D"la=
zy" srcset=3D"https://alsnewstoday.com/wp-content/uploads/2022/09/Clinical=
TrialsClipboard.png 700w=2C https://alsnewstoday.com/wp-content/uploads/20=
22/09/ClinicalTrialsClipboard-380x190.png 380w" sizes=3D"(max-width: 700px=
) 100vw=2C 700px" border=3D"0"></a><p style=3D"margin: 10px 0;padding: 0;m=
so-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-=
adjust: 100%;color: #202020;font-family: Helvetica;font-size: 16px;line-he=
ight: 150%;text-align: left;">Neurosense Therapeutics is revamping its dev=
elopment plan for PrimeC=2C the company&#8217;s experimental oral therapy=
 for amyotrophic lateral sclerosis (ALS). The updated plan includes a new=
 study that will directly compare PrimeC against an approved ALS treatment=
=2C as well as a restructured Phase 3 trial and analyses of existing data=
 using artificial intelligence (AI). With these [&#8230;]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-fa=
mily: Helvetica;font-size: 16px;line-height: 150%;text-align: left;">The p=
ost <a href=3D"https://us.list-manage.com/11ijUEt5lVx?e=3D006462e992&c2id=
=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DtGnyoiWWOPQot6VvPalWtESbbR4V3kwM_pHWgS2w75D29OfiHfP_-RW1DQCI" style=3D"mso-line-he=
ight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 10=
0%;color: #1e2559;font-weight: normal;text-decoration: underline;">Revampe=
d plan aims to hasten US approval of treatment for ALS</a> appeared first=
 on <a href=3D"https://us.list-manage.com/MCAbsacRGyB?e=3D006462e992&c2id=
=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D2lZvV2h8mdMP9QEAt6QWqA9AzLqax6y_QUxYn_PK9Jn_RMNN3fDEK6y0LlpS" style=3D"mso-line-he=
ight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 10=
0%;color: #1e2559;font-weight: normal;text-decoration: underline;">ALS New=
s Today</a>.</p></div>
=09=09=09<!-- Continue Reading Button (Filled Blue) --><a href=3D"https://=
us.list-manage.com/5hJgjwUj1xx?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D94sDamt29vNlE9a6BxjcbOavO293XFENd2Btx2gmEqJjPVOZ4IyMUrna25pVW-yUkcTaR1iRl2SesqP8DmSiLf3o-Q=3D=3D" style=3D"display: inline-block;padding: 12p=
x 24px;background-color: #1754FF;color: #ffffff;font-family: 'Helvetica Ne=
ue'=2C Helvetica=2C Arial=2C sans-serif;font-size: 14px;font-weight: 600;t=
ext-decoration: none;border-radius: 6px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">Continue Reading <=
/a></td>
=09=09</tr>
=09</tbody>
</table>

                        </td>
                    </tr>
                </tbody></table>
=09=09=09=09<!--[if mso]>
=09=09=09=09</td>
=09=09=09=09<![endif]-->

=09=09=09=09<!--[if mso]>
=09=09=09=09</tr>
=09=09=09=09</table>
=09=09=09=09<![endif]-->
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</table></td>
                            </tr>
                            <tr>
                                <td valign=3D"top" id=3D"templateColumns"=
 style=3D"background: #ffffff none no-repeat center/cover;mso-line-height-=
rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;ba=
ckground-color: #ffffff;background-image: none;background-repeat: no-repea=
t;background-position: center;background-size: cover;border-top: 0;border-=
bottom: 0;padding-top: 0;padding-bottom: 0;">
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ellspacing=3D"0" cellpadding=3D"0" width=3D"600" style=3D"width:600px;">
                                    <tr>
                                    <td align=3D"center" valign=3D"top" wi=
dth=3D"300" style=3D"width:300px;">
                                    <![endif]-->
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lpadding=3D"0" cellspacing=3D"0" width=3D"300" class=3D"columnWrapper" sty=
le=3D"border-collapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0p=
t;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;float: left;">
                                        <tr>
                                            <td valign=3D"top" class=3D"co=
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</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnTextBlock" style=3D"min-width: 100%;border-collapse: coll=
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g-top: 9px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webki=
t-text-size-adjust: 100%;">
              =09<!--[if mso]>
=09=09=09=09<table align=3D"left" border=3D"0" cellspacing=3D"0" cellpaddi=
ng=3D"0" width=3D"100%" style=3D"width:100%;">
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=09=09=09=09<![endif]-->
=09=09=09
=09=09=09=09<!--[if mso]>
=09=09=09=09<td valign=3D"top" width=3D"600" style=3D"width:600px;">
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                        <td valign=3D"top" class=3D"mcnTextContent" style=
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8px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;word-break: break-word;color: #222222;font-family: Helve=
tica;font-size: 16px;line-height: 200%;text-align: left;">

                            <div style=3D"text-align: center;"><span style=
=3D"font-size:14px"><em><strong>Follow us on social media for exclusive co=
ntent=2C and visit our website to learn about our Advocacy Partners: The A=
LS Association=2C Muscular Dystrophy Association=2C and The ALS Network</s=
trong></em></span></div>

                        </td>
                    </tr>
                </tbody></table>
=09=09=09=09<!--[if mso]>
=09=09=09=09</td>
=09=09=09=09<![endif]-->

=09=09=09=09<!--[if mso]>
=09=09=09=09</tr>
=09=09=09=09</table>
=09=09=09=09<![endif]-->
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=3D"mcnFollowContent" style=3D"border-collapse: collapse;mso-table-lspace:=
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op: 9px;padding-right: 9px;padding-left: 9px;mso-line-height-rule: exactly=
;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
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ce: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size=
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                            <tbody><tr>
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size-adjust: 100%;">
                                    <!--[if mso]>
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ellspacing=3D"0" cellpadding=3D"0">
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                                        <!--[if mso]>
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                                                <tbody><tr>
                                                    <td valign=3D"top" sty=
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                                                        <table border=3D"0=
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                                                            <tbody><tr>
                                                                <td align=
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                                                                    <table=
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                                                                        <t=
body><tr>

                                                                         =
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                                                    </td>
                                                </tr>
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                                        <!--[if mso]>
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                                        <![endif]-->

                                        <!--[if mso]>
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                                            <table align=3D"left" border=
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                                                <tbody><tr>
                                                    <td valign=3D"top" sty=
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y;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;" class=3D"mcn=
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                                                        <table border=3D"0=
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                                                            <tbody><tr>
                                                                <td align=
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padding-bottom: 5px;padding-left: 9px;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
                                                                    <table=
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ft;">
                                                                        <t=
body><tr>

                                                                         =
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                                                                         =
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                                                            </tr>
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                                                    </td>
                                                </tr>
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                                        <!--[if mso]>
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                                        <![endif]-->

                                        <!--[if mso]>
                                        <td align=3D"center" valign=3D"top=
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                                            <table align=3D"left" border=
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                                                <tbody><tr>
                                                    <td valign=3D"top" sty=
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y;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;" class=3D"mcn=
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                                                            <tbody><tr>
                                                                <td align=
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xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
                                                                    <table=
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ft;">
                                                                        <t=
body><tr>

                                                                         =
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                                                                         =
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                                                                    </tbod=
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                                                                </td>
                                                            </tr>
                                                        </tbody></table>
                                                    </td>
                                                </tr>
                                            </tbody></table>

                                        <!--[if mso]>
                                        </td>
                                        <![endif]-->

                                        <!--[if mso]>
                                        <td align=3D"center" valign=3D"top=
">
                                        <![endif]-->


                                            <table align=3D"left" border=
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table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100=
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                                                <tbody><tr>
                                                    <td valign=3D"top" sty=
le=3D"padding-right: 10px;padding-bottom: 9px;mso-line-height-rule: exactl=
y;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;" class=3D"mcn=
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le-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;"=
>
                                                            <tbody><tr>
                                                                <td align=
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padding-bottom: 5px;padding-left: 9px;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
                                                                    <table=
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ft;">
                                                                        <t=
body><tr>

                                                                         =
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                                                                </td>
                                                            </tr>
                                                        </tbody></table>
                                                    </td>
                                                </tr>
                                            </tbody></table>

                                        <!--[if mso]>
                                        </td>
                                        <![endif]-->

                                        <!--[if mso]>
                                        <td align=3D"center" valign=3D"top=
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                                            <table align=3D"left" border=
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table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100=
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                                                <tbody><tr>
                                                    <td valign=3D"top" sty=
le=3D"padding-right: 10px;padding-bottom: 9px;mso-line-height-rule: exactl=
y;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;" class=3D"mcn=
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le-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;"=
>
                                                            <tbody><tr>
                                                                <td align=
=3D"left" valign=3D"middle" style=3D"padding-top: 5px;padding-right: 10px;=
padding-bottom: 5px;padding-left: 9px;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
                                                                    <table=
 align=3D"left" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"=
" style=3D"border-collapse: collapse;mso-table-lspace: 0pt;mso-table-rspac=
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ft;">
                                                                        <t=
body><tr>

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