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** MDA Engage: Patients can take steps to improve breathing issues (https:=
//us.list-manage.com/57KutuIHIZg?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DS6rvwjlaSqEk4tQdiKqMqbTdLa86SfmLFWsGX7wIke51xI2Uw2g_EhW79LPYDMEIyyRq6pDesVJ1xmE9T115HYxweg=3D=3D)
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A progressive decline in lung function is unavoidable for many people with=
 neuromuscular conditions such as amyotrophic lateral sclerosis (ALS)=2C b=
ut there are steps that patients can take to ease breathing issues and imp=
rove quality of life. =E2=80=9CWe can=E2=80=99t really change the progress=
ion=2C=E2=80=9D said James Rowley=2C MD=2C a pulmonologist at Rush Univers=
ity Medical Center in Chicago. [=E2=80=A6]

The post MDA Engage: Patients can take steps to improve breathing issues (=
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** Low muscle mass may help predict survival in people with ALS (https://u=
s.list-manage.com/jh9HRmCSe3F?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3Dbz9BgB_e8LPcD4GTgBSTX6r2gCfp5Crh48JSocRq4wTOA4kKvcKCA-zOSc_IFdbpK6V1ZmL5i7juTQ57v6DAzA1VnA=3D=3D)
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Low muscle mass in the arms and legs=2C as well as sarcopenia (low muscle=
 mass and strength)=2C were each linked to poorer survival in people with=
 amyotrophic lateral sclerosis (ALS)=2C a small prospective study in Spain=
 found. =E2=80=9CThese findings suggest that muscle mass may provide progn=
ostic information complementary to conventional clinical markers=2C=E2=80=
=9D the researchers wrote. [=E2=80=A6]

The post Low muscle mass may help predict survival in people with ALS (htt=
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** The changing of the seasons reminds me of life with ALS (https://us.lis=
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Fall has arrived=2C and the days are cooler here on Michigan=E2=80=99s Kew=
eenaw Peninsula. The maples are showing hints of red=2C and we haven=E2=80=
=99t seen a ruby-throated hummingbird for a few weeks. I suspect they=E2=
=80=99ve all headed south for the winter. Last spring=2C we put decoy swan=
s on the pond to ward off Canadian geese. The [=E2=80=A6]

The post The changing of the seasons reminds me of life with ALS (https://=
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** Targeted therapy may improve function=2C survival in FUS-ALS (https://u=
s.list-manage.com/JKYfy1fuhd1?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DQj0L2SyzWEH8zY4YmDV5q6SUGsmTHetaIftPJZl4CedYW1BgnOhQMxvJFC8EVdZLG8zmfMmzTVGJVz4kMSgqVvLkJQ=3D=3D)
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Otsuka Pharmaceutical=E2=80=99s experimental therapy ulefnersen improved a=
 combined measure of function and survival compared with a placebo in peop=
le with amyotrophic lateral sclerosis (ALS) caused by mutations in the FUS=
 gene. That=E2=80=99s according to top-line data from the first part of th=
e ongoing=2C global Phase 3 FUSION clinical trial (NCT04768972)=2C which e=
nrolled 89 people with FUS-ALS. [=E2=80=A6]

The post Targeted therapy may improve function=2C survival in FUS-ALS (htt=
ps://us.list-manage.com/Tq4SoCAopCI?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3Dr3Z3HjlgtSJq4BPuW2Ih8rHpnm-XuZ9cVNkgv81yI2TXLixmNLv9WVUBsC3W) appeared first on ALS N=
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pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
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                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding: 0px 18px 9px;color: #222222;font-family: Arial=2C &quot;Helve=
tica Neue&quot;=2C Helvetica=2C sans-serif;font-size: 16px;font-weight: no=
rmal;text-align: left;mso-line-height-rule: exactly;-ms-text-size-adjust:=
 100%;-webkit-text-size-adjust: 100%;word-break: break-word;line-height: 1=
50%;">

                            <!-- Section Label -->
<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
margin-bottom: 16px;border-collapse: collapse;mso-table-lspace: 0pt;mso-ta=
ble-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;=
" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"background-color: #1754ff;border-radius: 2px;mso-lin=
e-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust=
: 100%;" width=3D"4">&nbsp;</td>
=09=09=09<td style=3D"padding-left: 8px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<p style=3D"margin: 0px;font-family: &quot;Helvetica Neue&quot;=
=2C Helvetica=2C Arial=2C sans-serif;font-weight: 700;text-transform: uppe=
rcase;letter-spacing: 1px;padding: 0;mso-line-height-rule: exactly;-ms-tex=
t-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #222222;font-siz=
e: 18px;line-height: 150%;text-align: left;"><font color=3D"#000000"><span=
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an></font></p>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>
<!-- Intro Text --><!-- Feed Block --><br>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/x6MqWCjJ=
sQ8?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DaSzQbZ0orduwH0PaU5rIcjYNtFlgn2TY0xI6frpNEFeD97gnw3wPrGDG9rwWOarXxDEXUr3q0xrNn3NeQfZ7AqS3XA=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">MDA Engage: Patients can take steps to impro=
ve breathing issues</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/ovy_UL6K=
vr0?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D4I24dQghh6Y54JbQMvl8Kg193KC4O3aCQBgbHeInuRSCDnkGXg3niyZ5-2pwcpuJOtM91CY7keH5kAsEY0TjMJ5Udg=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">Low muscle mass may help predict survival in=
 people with ALS</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/esczJmx4=
RjK?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DNQFWS_IUr--hvEG22UJuPEQjA-BLLTaN3wLQP3uU0KRWUs9VnGqoUqLRn3mILNTcGPAfl7Sf1N8_062EGOb4z19pXQ=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">Targeted therapy may improve function=2C sur=
vival in FUS-ALS</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

                        </td>
                    </tr>
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=09=09=09=09<!--[if mso]>
=09=09=09=09</td>
=09=09=09=09<![endif]-->

=09=09=09=09<!--[if mso]>
=09=09=09=09</tr>
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=09=09=09=09<![endif]-->
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table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100=
%;">
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                        <td style=3D"mso-line-height-rule: exactly;-ms-tex=
t-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
                            <span></span>
                        </td>
                    </tr>
                </tbody></table>
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g-top: 9px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webki=
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              =09<!--[if mso]>
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=09=09=09=09<tr>
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=09=09=09
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=09=09=09=09<td valign=3D"top" width=3D"NaN" style=3D"width:NaNpx;">
=09=09=09=09<![endif]-->
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pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
                    <tbody><tr>

                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding: 0px 18px 9px;color: #222222;font-family: Arial=2C &quot;Helve=
tica Neue&quot;=2C Helvetica=2C sans-serif;font-size: 16px;font-weight: no=
rmal;text-align: left;mso-line-height-rule: exactly;-ms-text-size-adjust:=
 100%;-webkit-text-size-adjust: 100%;word-break: break-word;line-height: 1=
50%;">

                            <!-- Section Label -->
<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
margin-bottom: 16px;border-collapse: collapse;mso-table-lspace: 0pt;mso-ta=
ble-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;=
" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"background-color: #05D3AB;border-radius: 2px;mso-lin=
e-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust=
: 100%;" width=3D"4">&nbsp;</td>
=09=09=09<td style=3D"padding-left: 8px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<p style=3D"margin: 0px;font-family: &quot;Helvetica Neue&quot;=
=2C Helvetica=2C Arial=2C sans-serif;font-weight: 700;text-transform: uppe=
rcase;letter-spacing: 1px;padding: 0;mso-line-height-rule: exactly;-ms-tex=
t-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #222222;font-siz=
e: 18px;line-height: 150%;text-align: left;"><font color=3D"#000000"><span=
 style=3D"font-size:15px">Community Voices</span></font></p>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>
<!-- Intro Text --><!-- Feed Block --><br>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/6frSA3i5=
RmR?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D6TohZT2lNPMtN5JYawUyw-llM5UZcF9TONtDobSgn6AYm-TAljQHHJeXVFfkNtXAvu7XX9o0gOIAMaQkUKTFhU4byQ=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">The changing of the seasons reminds me of li=
fe with ALS</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/dCn8LEQC=
Lvl?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DPTTz9vsRRiuX_G65OCP3K-hG-LiKm96PeihzVC40LPcGuza2FAlTWsSI3pqOwvhSbxPnKl334SCeq7vNqfUkvX22RA=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">Building small habits through exercise to st=
ay strong with ALS</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/EevqvYbR=
7Ie?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DN5EnaUsHKO47L7-xl9hEa_5_UOl28yuHohVjLHd3YiT6PTORLspqkUJPcvWtqZrTojmONVWI44_AxiH8YMxW83G8Cw=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">Guest Voice: Love protects our marriage in t=
he =E2=80=98Suffering Wars=E2=80=99 of ALS</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

                        </td>
                    </tr>
                </tbody></table>
=09=09=09=09<!--[if mso]>
=09=09=09=09</td>
=09=09=09=09<![endif]-->

=09=09=09=09<!--[if mso]>
=09=09=09=09</tr>
=09=09=09=09</table>
=09=09=09=09<![endif]-->
            </td>
        </tr>
    </tbody>
</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnDividerBlock" style=3D"min-width: 100%;border-collapse: c=
ollapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust:=
 100%;-webkit-text-size-adjust: 100%;table-layout: fixed !important;">
    <tbody class=3D"mcnDividerBlockOuter">
        <tr>
            <td class=3D"mcnDividerBlockInner" style=3D"min-width: 100%;pa=
dding: 5px 18px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-=
webkit-text-size-adjust: 100%;">
                <table class=3D"mcnDividerContent" border=3D"0" cellpaddin=
g=3D"0" cellspacing=3D"0" width=3D"100%" style=3D"min-width: 100%;border-t=
op: 2px solid #EAEAEA;border-collapse: collapse;mso-table-lspace: 0pt;mso-=
table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100=
%;">
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                        <td style=3D"mso-line-height-rule: exactly;-ms-tex=
t-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
                            <span></span>
                        </td>
                    </tr>
                </tbody></table>
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</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnTextBlock" style=3D"min-width: 100%;border-collapse: coll=
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g-top: 9px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webki=
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              =09<!--[if mso]>
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                        <td valign=3D"top" class=3D"mcnTextContent" style=
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tica Neue&quot;=2C Helvetica=2C sans-serif;font-size: 16px;font-weight: no=
rmal;text-align: left;mso-line-height-rule: exactly;-ms-text-size-adjust:=
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50%;">

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<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
margin-bottom: 16px;border-collapse: collapse;mso-table-lspace: 0pt;mso-ta=
ble-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;=
" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"background-color: #1754ff;border-radius: 2px;mso-lin=
e-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust=
: 100%;" width=3D"4">&nbsp;</td>
=09=09=09<td style=3D"padding-left: 8px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<p style=3D"margin: 0px;font-family: &quot;Helvetica Neue&quot;=
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rcase;letter-spacing: 1px;padding: 0;mso-line-height-rule: exactly;-ms-tex=
t-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #222222;font-siz=
e: 18px;line-height: 150%;text-align: left;"><font color=3D"#000000"><span=
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=09=09=09</td>
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=09</tbody>
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<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
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=09<tbody>
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=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
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DML?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DXCNtXKUx8RcBodx9VGbzW3W4duia5uyF0k63YYaR8h1i3udjQwHY4y0PB7EgYuEi_Bu42XsmigV96PxmFXGhU6DxiQ=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">Dressing STick</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
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=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/jVEMUpjN=
EoN?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D7O99-xsn4ZftCRnW6kXFQylMT1rNWRlxa8xkZV51EuZv2w38NPRrXWkCRaO5zjjndBe01FhWVOcm3e0MiJ_FCoHOPA=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">For PALS: Do you still drive?</a></h3>
=09=09=09</td>
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0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
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                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding: 0px 18px 9px;color: #222222;font-family: Arial=2C &quot;Helve=
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rmal;text-align: left;mso-line-height-rule: exactly;-ms-text-size-adjust:=
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50%;">

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<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
margin-bottom: 16px;border-collapse: collapse;mso-table-lspace: 0pt;mso-ta=
ble-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;=
" width=3D"100%">
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=09=09=09<td style=3D"background-color: #05D3AB;border-radius: 2px;mso-lin=
e-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust=
: 100%;" width=3D"4">&nbsp;</td>
=09=09=09<td style=3D"padding-left: 8px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<p style=3D"margin: 0px;font-family: &quot;Helvetica Neue&quot;=
=2C Helvetica=2C Arial=2C sans-serif;font-weight: 700;text-transform: uppe=
rcase;letter-spacing: 1px;padding: 0;mso-line-height-rule: exactly;-ms-tex=
t-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-siz=
e: 16px;line-height: 150%;text-align: left;"><font color=3D"#000000"><span=
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<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/HcZGqsdj=
42u?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DfnpW6w45fcHC-IfbOI9KNmoTHmuMDSPex8r4tIcBCEyO4m9CtwiTzn7Vp6GfI1-ENeEg2T7wHPyKg4LOKsa7Fe18jw=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">ALS stages and progression timeline</a></h3>
=09=09=09</td>
=09=09</tr>
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</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #F5F5F5;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
=09=09=09<h3 style=3D"margin: 0;font-family: 'Helvetica Neue'=2C Helvetica=
=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color: #000000;li=
ne-height: 1.3;display: block;padding: 0;font-style: normal;letter-spacing=
: normal;text-align: left;"><a href=3D"https://us.list-manage.com/Ng9Jx3Ha=
hs9?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DZIOarQSHz4PZOgQX-gNYcoINx9s0sg5SOLc7t3ijLXmQ_XvP-SBb6UrEldD1lK0V9C_cxk7VTnIhtGOTpHYllTT7CQ=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-height-rule: ex=
actly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;font-weigh=
t: normal;" target=3D"_blank">Demystifying ALS: Separating fact from ficti=
on</a></h3>
=09=09=09</td>
=09=09</tr>
=09</tbody>
</table>

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00%" class=3D"mcnDividerBlock" style=3D"min-width: 100%;border-collapse: c=
ollapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust:=
 100%;-webkit-text-size-adjust: 100%;table-layout: fixed !important;">
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dding: 5px 18px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-=
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g=3D"0" cellspacing=3D"0" width=3D"100%" style=3D"min-width: 100%;border-t=
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table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100=
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00%" class=3D"mcnTextBlock" style=3D"min-width: 100%;border-collapse: coll=
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g-top: 9px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webki=
t-text-size-adjust: 100%;">
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=09=09=09=09<table align=3D"left" border=3D"0" cellspacing=3D"0" cellpaddi=
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=09=09=09=09<![endif]-->
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pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
nTextContentContainer">
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                        <td valign=3D"top" class=3D"mcnTextContent" style=
=3D"padding-top: 0;padding-right: 18px;padding-bottom: 9px;padding-left: 1=
8px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;word-break: break-word;color: #202020;font-family: Helve=
tica;font-size: 16px;line-height: 150%;text-align: left;">


<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #ffffff;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;"><!-- Article Title (Bo=
ld) -->
=09=09=09<h2 style=3D"margin: 0 0 12px 0;font-family: 'Helvetica Neue'=2C=
 Helvetica=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color:=
 #000000;line-height: 1.3;display: block;padding: 0;font-style: normal;let=
ter-spacing: normal;text-align: left;"><a href=3D"https://us.list-manage.c=
om/pHwknlwd4bz?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DUCptZXkhDgyC6-dciUxLbTvsLT7JEbW56bit7LzG1nIFffpoYIMWDiiF-xherG45xMJbyclkp9tyO64GvLL22xsY9g=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-heig=
ht-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%=
;font-weight: normal;"><strong>MDA Engage: Patients can take steps to impr=
ove breathing issues</strong> </a></h2>
=09=09=09<!-- Article Content Preview (Black=2C 16px) -->

=09=09=09<div style=3D"font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C sans-serif; font-size: 14px; color: #000000; line-height: 1.6; margin:=
0 0 16px 0;"><a href=3D"https://us.list-manage.com/Cba1Trq4U4o?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DXLHg3BrZ_ZQfGmCXHn-JW01CIvw0ZIzmNWvcsUmCzItDeTgye-egSAnpT2_q" title=3D"MD=
A Engage: Patients can take steps to improve breathing issues" rel=3D"nofo=
llow" style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-w=
ebkit-text-size-adjust: 100%;color: #1e2559;font-weight: normal;text-decor=
ation: underline;"><img width=3D"800" src=3D"https://alsnewstoday.com/wp-c=
ontent/uploads/2026/03/MDA-9-1-800x286.png" class=3D"webfeedsFeaturedVisua=
l wp-post-image mcRssImage" alt=3D"An illustration shows a muscle with the=
 letters &quot;MDA&quot; at the top." style=3D"max-width: 100%;width: 100%=
;padding-bottom: 0;display: inline;vertical-align: bottom;border: 0;height=
: auto;outline: none;text-decoration: none;-ms-interpolation-mode: bicubic=
;" link_thumbnail=3D"1" decoding=3D"async" loading=3D"lazy" srcset=3D"http=
s://alsnewstoday.com/wp-content/uploads/2026/03/MDA-9-1-800x286.png 800w=
=2C https://alsnewstoday.com/wp-content/uploads/2026/03/MDA-9-1-380x136.pn=
g 380w=2C https://alsnewstoday.com/wp-content/uploads/2026/03/MDA-9-1-768x=
274.png 768w=2C https://alsnewstoday.com/wp-content/uploads/2026/03/MDA-9-=
1.png 1400w" sizes=3D"(max-width: 800px) 100vw=2C 800px" border=3D"0"></a>=
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-fa=
mily: Helvetica;font-size: 16px;line-height: 150%;text-align: left;">A pro=
gressive decline in lung function is unavoidable for=C2=A0many people with=
 neuromuscular conditions such as amyotrophic lateral sclerosis (ALS)=2C b=
ut there are steps that patients can take to ease breathing issues and imp=
rove quality of life. =E2=80=9CWe can=E2=80=99t really change the progress=
ion=2C=E2=80=9D said James Rowley=2C MD=2C a pulmonologist at Rush Univers=
ity Medical Center in Chicago. [&#8230;]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-fa=
mily: Helvetica;font-size: 16px;line-height: 150%;text-align: left;">The p=
ost <a href=3D"https://us.list-manage.com/ZGXTLh8HHqZ?e=3D006462e992&c2id=
=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DN9qiVfwxiNYyuG7GF9XrjRiivLZeXInw9ANhrTndKxNtuCy4xzCEQYnDUS8z" style=3D"mso-line-he=
ight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 10=
0%;color: #1e2559;font-weight: normal;text-decoration: underline;">MDA Eng=
age: Patients can take steps to improve breathing issues</a> appeared firs=
t on <a href=3D"https://us.list-manage.com/PWVZTVmS6lE?e=3D006462e992&c2i=
d=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DeNNoTBBzPbjo8RbpZ-qxNfUECyc-lZDFodliXuJgrH09o97mN0U3OIUwqNrX" style=3D"mso-line-h=
eight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 1=
00%;color: #1e2559;font-weight: normal;text-decoration: underline;">ALS Ne=
ws Today</a>.</p></div>
=09=09=09<!-- Continue Reading Button (Filled Blue) --><a href=3D"https://=
us.list-manage.com/2Rm2mHB0_mY?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DVX0OSDWJkHwfyuk-wO7CtLKPJK62SJ7QV-V-MiT4_1XovJGADgMNE9fnR-T9yyiNZBF07Cg_ToilrPoxuoueFwM_jg=3D=3D" style=3D"display: inline-block;padding: 12p=
x 24px;background-color: #1754FF;color: #ffffff;font-family: 'Helvetica Ne=
ue'=2C Helvetica=2C Arial=2C sans-serif;font-size: 14px;font-weight: 600;t=
ext-decoration: none;border-radius: 6px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">Continue Reading <=
/a></td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #ffffff;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;"><!-- Article Title (Bo=
ld) -->
=09=09=09<h2 style=3D"margin: 0 0 12px 0;font-family: 'Helvetica Neue'=2C=
 Helvetica=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color:=
 #000000;line-height: 1.3;display: block;padding: 0;font-style: normal;let=
ter-spacing: normal;text-align: left;"><a href=3D"https://us.list-manage.c=
om/Jn9OmtiAxVV?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DKA2hNFXNb4qCfD2GEFWfBFZdm_az-nTixp53RbGhPlZlpY_JzcA8DtM_AiO0rIw_2hn3LcJG3wAFTbMQJcnzkLPz_Q=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-heig=
ht-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%=
;font-weight: normal;"><strong>Low muscle mass may help predict survival i=
n people with ALS</strong> </a></h2>
=09=09=09<!-- Article Content Preview (Black=2C 16px) -->

=09=09=09<div style=3D"font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C sans-serif; font-size: 14px; color: #000000; line-height: 1.6; margin:=
0 0 16px 0;"><a href=3D"https://us.list-manage.com/7NSwgOvOvbl?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DkVVHZpWECReX1XJCeaW10lYEhb-vkdXa2W6XNkHXe1rZyuSbPdWvrPcln_-s" title=3D"Lo=
w muscle mass may help predict survival in people with ALS" rel=3D"nofollo=
w" style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webk=
it-text-size-adjust: 100%;color: #1e2559;font-weight: normal;text-decorati=
on: underline;"><img width=3D"700" src=3D"https://alsnewstoday.com/wp-cont=
ent/uploads/2022/11/Muscle.png" class=3D"webfeedsFeaturedVisual wp-post-im=
age mcRssImage" alt=3D"An illustration provides an inside view of the stru=
cture of a human muscle." style=3D"max-width: 100%;width: 100%;padding-bot=
tom: 0;display: inline;vertical-align: bottom;border: 0;height: auto;outli=
ne: none;text-decoration: none;-ms-interpolation-mode: bicubic;" link_thum=
bnail=3D"1" decoding=3D"async" loading=3D"lazy" srcset=3D"https://alsnewst=
oday.com/wp-content/uploads/2022/11/Muscle.png 700w=2C https://alsnewstoda=
y.com/wp-content/uploads/2022/11/Muscle-380x190.png 380w" sizes=3D"(max-wi=
dth: 700px) 100vw=2C 700px" border=3D"0"></a><p style=3D"margin: 10px 0;pa=
dding: 0;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-=
text-size-adjust: 100%;color: #202020;font-family: Helvetica;font-size: 16=
px;line-height: 150%;text-align: left;">Low muscle mass in the arms and le=
gs=2C as well as sarcopenia (low muscle mass and strength)=2C were each li=
nked to poorer survival in people with amyotrophic lateral sclerosis (ALS)=
=2C a small prospective study in Spain found. =E2=80=9CThese findings sugg=
est that muscle mass may provide prognostic information complementary to c=
onventional clinical markers=2C=E2=80=9D the researchers wrote. [&#8230;]=
</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-fa=
mily: Helvetica;font-size: 16px;line-height: 150%;text-align: left;">The p=
ost <a href=3D"https://us.list-manage.com/Dxujyf9kbaW?e=3D006462e992&c2id=
=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D6-E8-tv83AviQsSIHTWRMQurL5PuZ8AyjTetFk91yT-w2CzNwE5OXg4EIXbo" style=3D"mso-line-he=
ight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 10=
0%;color: #1e2559;font-weight: normal;text-decoration: underline;">Low mus=
cle mass may help predict survival in people with ALS</a> appeared first o=
n <a href=3D"https://us.list-manage.com/10Y5LlUme0u?e=3D006462e992&c2id=
=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DbHkN0NCPQghfELNMStw63-uqTTCBpEY2HhubTgEwQIvdnBO5qi5A2sq1T-11" style=3D"mso-line-he=
ight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 10=
0%;color: #1e2559;font-weight: normal;text-decoration: underline;">ALS New=
s Today</a>.</p></div>
=09=09=09<!-- Continue Reading Button (Filled Blue) --><a href=3D"https://=
us.list-manage.com/VT2t658tR3j?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DJubJKILFc63uJTvVOr78jeSM05Tq-dwOBj6Y0wzrQiX5GyI1spJnCgo5fvhpgKOlJp1tGraSWl98T_K1g4TCXNT3EQ=3D=3D" style=3D"display: inline-block;padding: 12p=
x 24px;background-color: #1754FF;color: #ffffff;font-family: 'Helvetica Ne=
ue'=2C Helvetica=2C Arial=2C sans-serif;font-size: 14px;font-weight: 600;t=
ext-decoration: none;border-radius: 6px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">Continue Reading <=
/a></td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #ffffff;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;"><!-- Article Title (Bo=
ld) -->
=09=09=09<h2 style=3D"margin: 0 0 12px 0;font-family: 'Helvetica Neue'=2C=
 Helvetica=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color:=
 #000000;line-height: 1.3;display: block;padding: 0;font-style: normal;let=
ter-spacing: normal;text-align: left;"><a href=3D"https://us.list-manage.c=
om/ta4yFhT6gIK?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DXSxTozlL6BfkuM4UePyr4hPcrm23u8avDzKg2G9RItl7Z_SMwbZiSk9U6rhMPKlOt97bIPEBOw3O1Eg-xFDFIN3FuA=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-heig=
ht-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%=
;font-weight: normal;"><strong>The changing of the seasons reminds me of l=
ife with ALS</strong> </a></h2>
=09=09=09<!-- Article Content Preview (Black=2C 16px) -->

=09=09=09<div style=3D"font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C sans-serif; font-size: 14px; color: #000000; line-height: 1.6; margin:=
0 0 16px 0;"><a href=3D"https://us.list-manage.com/ctFptG0RNve?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DWDT9Ge44WUry2FZQL-DgN7mwdDuLMI8qwIv_lzsau5vzZzMmFZ2MnudAqbqC" title=3D"Th=
e changing of the seasons reminds me of life with ALS" rel=3D"nofollow" st=
yle=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-te=
xt-size-adjust: 100%;color: #1e2559;font-weight: normal;text-decoration: u=
nderline;"><img width=3D"800" src=3D"https://alsnewstoday.com/wp-content/u=
ploads/2020/09/kristinneva_joyfulsorrow-1024x384.jpg" class=3D"webfeedsFea=
turedVisual wp-post-image mcRssImage" alt=3D"Main graphic for &quot;Joyful=
 Sorrow&quot; column by Kristin Neva." style=3D"max-width: 100%;width: 100=
%;padding-bottom: 0;display: inline;vertical-align: bottom;border: 0;heigh=
t: auto;outline: none;text-decoration: none;-ms-interpolation-mode: bicubi=
c;" link_thumbnail=3D"1" decoding=3D"async" loading=3D"lazy" srcset=3D"htt=
ps://alsnewstoday.com/wp-content/uploads/2020/09/kristinneva_joyfulsorrow-=
1024x384.jpg 1024w=2C https://alsnewstoday.com/wp-content/uploads/2020/09/=
kristinneva_joyfulsorrow-300x113.jpg 300w=2C https://alsnewstoday.com/wp-c=
ontent/uploads/2020/09/kristinneva_joyfulsorrow-768x288.jpg 768w=2C https:=
//alsnewstoday.com/wp-content/uploads/2020/09/kristinneva_joyfulsorrow-120=
0x450.jpg 1200w=2C https://alsnewstoday.com/wp-content/uploads/2020/09/kri=
stinneva_joyfulsorrow.jpg 1400w" sizes=3D"(max-width: 800px) 100vw=2C 800p=
x" border=3D"0"></a><p style=3D"margin: 10px 0;padding: 0;mso-line-height-=
rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;co=
lor: #202020;font-family: Helvetica;font-size: 16px;line-height: 150%;text=
-align: left;">Fall has arrived=2C and the days are cooler here on Michiga=
n=E2=80=99s Keweenaw Peninsula. The maples are showing hints of red=2C and=
 we haven=E2=80=99t seen a ruby-throated hummingbird for a few weeks. I su=
spect they=E2=80=99ve all headed south for the winter. Last spring=2C we p=
ut decoy swans on the pond to ward off Canadian geese. The [&#8230;]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-fa=
mily: Helvetica;font-size: 16px;line-height: 150%;text-align: left;">The p=
ost <a href=3D"https://us.list-manage.com/1AHaxPLElLr?e=3D006462e992&c2id=
=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DZIe6P61QL_0zwU4Uyc6NHBKGbly78bf3e8uRSFygBCL0weFRoxLR6gskRHYA" style=3D"mso-line-he=
ight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 10=
0%;color: #1e2559;font-weight: normal;text-decoration: underline;">The cha=
nging of the seasons reminds me of life with ALS</a> appeared first on <a=
 href=3D"https://us.list-manage.com/s6rZTE2Jw8V?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DnSwWFagwi65gsBR5DtixlnP07gI7NlR5NLRCUtuO2Z_eYIEVwAq1Jmz6rIgQ" style=3D"mso-line-height-r=
ule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;col=
or: #1e2559;font-weight: normal;text-decoration: underline;">ALS News Toda=
y</a>.</p></div>
=09=09=09<!-- Continue Reading Button (Filled Blue) --><a href=3D"https://=
us.list-manage.com/15b4CpQreIr?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DjdODR91jIFig-TvyrPLljpslt0J7x5NDSngjV5hCuJRkfFoRrto6lLw7khxB_yhCLLk_O9D1PKhyGgfCCz35SWQN1w=3D=3D" style=3D"display: inline-block;padding: 12p=
x 24px;background-color: #1754FF;color: #ffffff;font-family: 'Helvetica Ne=
ue'=2C Helvetica=2C Arial=2C sans-serif;font-size: 14px;font-weight: 600;t=
ext-decoration: none;border-radius: 6px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">Continue Reading <=
/a></td>
=09=09</tr>
=09</tbody>
</table>

<table cellpadding=3D"0" cellspacing=3D"0" role=3D"presentation" style=3D"=
background-color: #ffffff;border-radius: 8px;margin-bottom: 12px;border-co=
llapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size=
-adjust: 100%;-webkit-text-size-adjust: 100%;" width=3D"100%">
=09<tbody>
=09=09<tr>
=09=09=09<td style=3D"padding: 16px;mso-line-height-rule: exactly;-ms-text=
-size-adjust: 100%;-webkit-text-size-adjust: 100%;"><!-- Article Title (Bo=
ld) -->
=09=09=09<h2 style=3D"margin: 0 0 12px 0;font-family: 'Helvetica Neue'=2C=
 Helvetica=2C Arial=2C sans-serif;font-size: 18px;font-weight: 700;color:=
 #000000;line-height: 1.3;display: block;padding: 0;font-style: normal;let=
ter-spacing: normal;text-align: left;"><a href=3D"https://us.list-manage.c=
om/148zTXIg2Ov?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DJ9CjDkgKJzAdxb5-uWQSA4isLFztstyoywJgX53ex_GO3tQQg2VK9wvILlAvjiHODeSTTvvRvIP1_-kk5Yp5_DB7LQ=3D=3D" style=3D"text-decoration: none;color: #000000;mso-line-heig=
ht-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%=
;font-weight: normal;"><strong>Targeted therapy may improve function=2C su=
rvival in FUS-ALS</strong> </a></h2>
=09=09=09<!-- Article Content Preview (Black=2C 16px) -->

=09=09=09<div style=3D"font-family: 'Helvetica Neue'=2C Helvetica=2C Arial=
=2C sans-serif; font-size: 14px; color: #000000; line-height: 1.6; margin:=
0 0 16px 0;"><a href=3D"https://us.list-manage.com/3rP_dIWQhwl?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DI44CZZB20Lk5Occ2-Mmqn7B7ZjgOlJ6RGgV7g6cc5sDWdPwK3Q5yvu8v6Qpk" title=3D"Ta=
rgeted therapy may improve function=2C survival in FUS-ALS" rel=3D"nofollo=
w" style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webk=
it-text-size-adjust: 100%;color: #1e2559;font-weight: normal;text-decorati=
on: underline;"><img width=3D"700" src=3D"https://alsnewstoday.com/wp-cont=
ent/uploads/2024/02/MegaphoneCone.png" class=3D"webfeedsFeaturedVisual wp-=
post-image mcRssImage" alt=3D"A person wearing a baseball cap makes an ann=
ouncement using a megaphone." style=3D"max-width: 100%;width: 100%;padding=
-bottom: 0;display: inline;vertical-align: bottom;border: 0;height: auto;o=
utline: none;text-decoration: none;-ms-interpolation-mode: bicubic;" link_=
thumbnail=3D"1" decoding=3D"async" loading=3D"lazy" srcset=3D"https://alsn=
ewstoday.com/wp-content/uploads/2024/02/MegaphoneCone.png 700w=2C https://=
alsnewstoday.com/wp-content/uploads/2024/02/MegaphoneCone-380x190.png 380w=
" sizes=3D"(max-width: 700px) 100vw=2C 700px" border=3D"0"></a><p style=3D=
"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-text-size-adj=
ust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-family: Helve=
tica;font-size: 16px;line-height: 150%;text-align: left;">Otsuka Pharmaceu=
tical=E2=80=99s experimental therapy ulefnersen improved a combined measur=
e of function and survival compared with a placebo in people with amyotrop=
hic lateral sclerosis (ALS)=C2=A0caused by mutations in the FUS gene. That=
&#8217;s according to top-line data from the first part of the ongoing=2C=
 global Phase 3 FUSION clinical trial (NCT04768972)=2C which enrolled 89 p=
eople with FUS-ALS. [&#8230;]</p>
<p style=3D"margin: 10px 0;padding: 0;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;color: #202020;font-fa=
mily: Helvetica;font-size: 16px;line-height: 150%;text-align: left;">The p=
ost <a href=3D"https://us.list-manage.com/QdJjJKHeWSN?e=3D006462e992&c2id=
=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DYwyzQSvm41v_zfLhAnxBSHOOtcJDVk40PZROV3URlm500U4aNquosFsmHOQa" style=3D"mso-line-he=
ight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 10=
0%;color: #1e2559;font-weight: normal;text-decoration: underline;">Targete=
d therapy may improve function=2C survival in FUS-ALS</a> appeared first o=
n <a href=3D"https://us.list-manage.com/YviqwU8aSm4?e=3D006462e992&c2id=
=3D6d8df1454ee901f23d2c8d3973c45e87&m=3DxNHQ2KJSyapuS86yYfoWwinQR0RermdT3IDfwy7S2xxnzgE15Hh9AHfrgs7I" style=3D"mso-line-he=
ight-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 10=
0%;color: #1e2559;font-weight: normal;text-decoration: underline;">ALS New=
s Today</a>.</p></div>
=09=09=09<!-- Continue Reading Button (Filled Blue) --><a href=3D"https://=
us.list-manage.com/142Z6qyi2DP?e=3D006462e992&c2id=3D6d8df1454ee901f23d2c8d3973c45e87&m=3D1sOqqUheFCF0tA2Iv3hEYuT9E74NlkZc2m_7BXT8NWgYIImq8u6n13aW2xUzbNWU2XoF9aFn_gpkJl5-Zig1QbFs8Q=3D=3D" style=3D"display: inline-block;padding: 12p=
x 24px;background-color: #1754FF;color: #ffffff;font-family: 'Helvetica Ne=
ue'=2C Helvetica=2C Arial=2C sans-serif;font-size: 14px;font-weight: 600;t=
ext-decoration: none;border-radius: 6px;mso-line-height-rule: exactly;-ms-=
text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">Continue Reading <=
/a></td>
=09=09</tr>
=09</tbody>
</table>

                        </td>
                    </tr>
                </tbody></table>
=09=09=09=09<!--[if mso]>
=09=09=09=09</td>
=09=09=09=09<![endif]-->

=09=09=09=09<!--[if mso]>
=09=09=09=09</tr>
=09=09=09=09</table>
=09=09=09=09<![endif]-->
            </td>
        </tr>
    </tbody>
</table></td>
                            </tr>
                            <tr>
                                <td valign=3D"top" id=3D"templateColumns"=
 style=3D"background: #ffffff none no-repeat center/cover;mso-line-height-=
rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;ba=
ckground-color: #ffffff;background-image: none;background-repeat: no-repea=
t;background-position: center;background-size: cover;border-top: 0;border-=
bottom: 0;padding-top: 0;padding-bottom: 0;">
                                    <!--[if (gte mso 9)|(IE)]>
                                    <table align=3D"center" border=3D"0" c=
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                        <td style=3D"mso-line-height-rule: exactly;-ms-tex=
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">
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</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnTextBlock" style=3D"min-width: 100%;border-collapse: coll=
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g-top: 9px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webki=
t-text-size-adjust: 100%;">
              =09<!--[if mso]>
=09=09=09=09<table align=3D"left" border=3D"0" cellspacing=3D"0" cellpaddi=
ng=3D"0" width=3D"100%" style=3D"width:100%;">
=09=09=09=09<tr>
=09=09=09=09<![endif]-->
=09=09=09
=09=09=09=09<!--[if mso]>
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=09=09=09=09<![endif]-->
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pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
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0%;-webkit-text-size-adjust: 100%;float: left;" width=3D"100%" class=3D"mc=
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                    <tbody><tr>

                        <td valign=3D"top" class=3D"mcnTextContent" style=
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8px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;word-break: break-word;color: #222222;font-family: Helve=
tica;font-size: 16px;line-height: 200%;text-align: left;">

                            <div style=3D"text-align: center;"><span style=
=3D"font-size:14px"><em><strong>Follow us on social media for exclusive co=
ntent=2C and visit our website to learn about our Advocacy Partners: The A=
LS Association=2C Muscular Dystrophy Association=2C and The ALS Network</s=
trong></em></span></div>

                        </td>
                    </tr>
                </tbody></table>
=09=09=09=09<!--[if mso]>
=09=09=09=09</td>
=09=09=09=09<![endif]-->

=09=09=09=09<!--[if mso]>
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=09=09=09=09</table>
=09=09=09=09<![endif]-->
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op: 9px;padding-right: 9px;padding-left: 9px;mso-line-height-rule: exactly=
;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
                        <table align=3D"center" border=3D"0" cellpadding=
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ce: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size=
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                            <tbody><tr>
                                <td align=3D"center" valign=3D"top" style=
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size-adjust: 100%;">
                                    <!--[if mso]>
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ellspacing=3D"0" cellpadding=3D"0">
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                                        <!--[if mso]>
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                                                <tbody><tr>
                                                    <td valign=3D"top" sty=
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                                                        <table border=3D"0=
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                                                            <tbody><tr>
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ft;">
                                                                        <t=
body><tr>

                                                                         =
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                                                    </td>
                                                </tr>
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                                        <!--[if mso]>
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                                        <![endif]-->

                                        <!--[if mso]>
                                        <td align=3D"center" valign=3D"top=
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                                            <table align=3D"left" border=
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                                                <tbody><tr>
                                                    <td valign=3D"top" sty=
le=3D"padding-right: 10px;padding-bottom: 9px;mso-line-height-rule: exactl=
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                                                        <table border=3D"0=
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                                                            <tbody><tr>
                                                                <td align=
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padding-bottom: 5px;padding-left: 9px;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
                                                                    <table=
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ft;">
                                                                        <t=
body><tr>

                                                                         =
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                                                                         =
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                                                                         =
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                                                                </td>
                                                            </tr>
                                                        </tbody></table>
                                                    </td>
                                                </tr>
                                            </tbody></table>

                                        <!--[if mso]>
                                        </td>
                                        <![endif]-->

                                        <!--[if mso]>
                                        <td align=3D"center" valign=3D"top=
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                                        <![endif]-->


                                            <table align=3D"left" border=
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                                                <tbody><tr>
                                                    <td valign=3D"top" sty=
le=3D"padding-right: 10px;padding-bottom: 9px;mso-line-height-rule: exactl=
y;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;" class=3D"mcn=
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                                                            <tbody><tr>
                                                                <td align=
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padding-bottom: 5px;padding-left: 9px;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
                                                                    <table=
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ft;">
                                                                        <t=
body><tr>

                                                                         =
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                                                                         =
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                                                                         =
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                                                                        </=
tr>
                                                                    </tbod=
y></table>
                                                                </td>
                                                            </tr>
                                                        </tbody></table>
                                                    </td>
                                                </tr>
                                            </tbody></table>

                                        <!--[if mso]>
                                        </td>
                                        <![endif]-->

                                        <!--[if mso]>
                                        <td align=3D"center" valign=3D"top=
">
                                        <![endif]-->


                                            <table align=3D"left" border=
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le=3D"display: inline;border-collapse: collapse;mso-table-lspace: 0pt;mso-=
table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100=
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                                                <tbody><tr>
                                                    <td valign=3D"top" sty=
le=3D"padding-right: 10px;padding-bottom: 9px;mso-line-height-rule: exactl=
y;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;" class=3D"mcn=
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le-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;"=
>
                                                            <tbody><tr>
                                                                <td align=
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padding-bottom: 5px;padding-left: 9px;mso-line-height-rule: exactly;-ms-te=
xt-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
                                                                    <table=
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ft;">
                                                                        <t=
body><tr>

                                                                         =
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                                                                         =
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                                                                </td>
                                                            </tr>
                                                        </tbody></table>
                                                    </td>
                                                </tr>
                                            </tbody></table>

                                        <!--[if mso]>
                                        </td>
                                        <![endif]-->

                                        <!--[if mso]>
                                        <td align=3D"center" valign=3D"top=
">
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                                            <table align=3D"left" border=
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table-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100=
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                                                <tbody><tr>
                                                    <td valign=3D"top" sty=
le=3D"padding-right: 10px;padding-bottom: 9px;mso-line-height-rule: exactl=
y;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;" class=3D"mcn=
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le-rspace: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;"=
>
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